Gloria Anderle
Department Chair
Department of Chemistry and Pharmaceutical Science
Fairleigh Dickinson University
Canada
Biography
Molecular dynamic simulation is particularly suited to study the affect of point mutations on collagen trimer stability of model native peptides. I am examining the changes in hydrogen bonding, dihedral angles and chain distance induced by the insertion of the mutation into the native sequence. In doing so, I hope to understand why the same mutation has such a diverse outcome depending on its location along the collagen trimer.
Research Interest
Current research interests include the molecular dynamic simulation in explicit water to determine protein structure.