Lorraine E. Chalifour
Associate Professor
Department of Medicine
Jewish General Hospital
Canada
Biography
Dr. Chalifour received her PhD in Biochemistry from the University of Manitoba in 1982. She moved to the Biological Chemistry Department at Harvard Medical School, Boston, where she completed a post-doctoral fellowship with Dr. Melvin DePamphilis. She then moved to Montreal and worked at the Biotechnology Research Institute before joining the Lady Davis Institute for Medical Research in 1990.
Research Interest
Dr. Chalifour’s research program utilizes molecular and physiological analyses to identify and characterize the impact of sex and sex hormones on the cardiovascular system in health and with pathology. Dr. Chalifour’s program is aimed at understanding the basic mechanisms whereby sex impacts normal cardiac function as well as the initiation and progression of cardiovascular disease. For example, echocardiographic analysis has identified unique cardiac structure and function features depending on the sex. Further, the pattern of expression of proteins involved in the control of calcium homeostasis is different in male and females and it is altered in cases of sex hormone deficiency.