Stephanie Lehoux

Biography

Dr. Stephanie Lehoux is an Associate Professor in the Department of Medicine at McGill University and a member of the Division of Experimental Medicine. She received her doctorate in Pharmacology from the University of Sherbrooke in 1997, followed by two post-doctoral fellowships at the Institut national de la santé et de la recherche médicale (France) and at the University of Rochester (New York). In 2001, she was recruited by the Centre national de la recherche scientifique (France), first as a Chargée de recherches, and more recently as Directeur de recherches. She established her laboratory studies on the molecular mechanisms associated with vascular mechanotransduction (the signal transduction cascades stimulated by changes in blood pressure or blood flow). 

Research Interest

Dr Lehoux’s research is aimed at understanding the factors that favour atherosclerotic lesion formation and progression. She is particularly interested in defining how endothelial dysfunction and immunomodulatory mechanisms interact, and how they relate to the hemodynamic environment of the plaque. Dr Lehoux’s experimental approach is multidisciplinary, combining molecular biology, biochemical, and physiological and histological techniques in a morphological and functional analysis of vascular biology. She has established a number of original tools and techniques that are used in in vivo, ex vivo and in vitro experiments.