Mary Jo Heeb
Professor
Molecular Medicine
The Scripps Research University
France
Biography
Ph.D. (Biochemistry), Georgetown University ,American Heart Association Established Investigator,Member, American Society of Hematology, American Society for Biochemistry and Molecular Biology, International Society for Thrombosis and Haemostasis Reviewer for Blood, Journal of Thrombosis and Haemostasis, Thrombosis and Haemostasis,and other journals.
Research Interest
Treatment, Drug design and therapeutics based on study of prostrate cancer and its treatment.
Publications
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Fernández, J.A.*, Heeb, M.J.*, Xu, X., Singh, L., Zlokovic, B.V., Griffin, J.H. Species-specific anticoagulant and mitogenic activities of murine protein S. Hematologica, 94:1721-1731, 2009. * These authors contributed equally.
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Heeb, M.J., Prashun, D., Griffin, J.H., Bouma, B.N. Plasma protein S contains zinc essential for efficient activated protein C-independent anticoagulant activity and binding to factor Xa, but not for efficient binding to tissue factor pathway inhibitor. FASEB J., 23:2244-2253, 2009.
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Burstyn-Cohen, T., Heeb, M.J., Lemke, G., Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis. J. Clin. Invest. 119:2942, 2009.