Dylan Spalding
Project Lead
EGA and Archive Infrastructure
European Molecular Biology Laboratory
Germany
Biography
Dylan's MSc from Reading University was based on an investigation of DNA alignment using hybrid evolutionary algorithms, and his PhD in Computer Science from Exeter University focused protein homology detection using kernel methods. In 2010 he joined the Peninsular College of Medicine and Dentistry as a bioinformatician, building a pipeline for exome sequence analysis with the primary aim of investigating monogenic causes of diabetes. Dylan joined EMBL-EBI in 2011 as part of the Database of Genomic Variants archive (DGVa) team, working with data on structural variation in all species. He become project lead for the European Genome-phenome Archive (EGA) in 2014.
Research Interest
Research based on an investigation of DNA alignment using hybrid evolutionary algorithms
Publications
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DbVar and DGVa: public archives for genomic structural variation. Lappalainen I, Lopez J, Skipper L, Hefferon T, Spalding JD, Garner J, Chen C, Maguire M, Corbett M, Zhou G, Paschall J, Ananiev V, Flicek P, Church DM. Nucleic Acids Res Volume 41 (2013) p.D936-41
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Consent Codes: Upholding Standard Data Use Conditions. Dyke SO, Philippakis AA, Rambla De Argila J, Paltoo DN, Luetkemeier ES, Knoppers BM, Brookes AJ, Spalding JD, Thompson M, Roos M, Boycott KM, Brudno M, Hurles M, Rehm HL, Matern A, Fiume M, Sherry ST. PLoS Genet Volume 12 (2016) p.e1005772
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Discovering and linking public omics data sets using the Omics Discovery Index. Perez-Riverol Y, Bai M, da Veiga Leprevost F, Squizzato S, Park YM, Haug K, Carroll AJ, Spalding D, Paschall J, Wang M, Del-Toro N, Ternent T, Zhang P, Buso N, Bandeira N, Deutsch EW, Campbell DS, Beavis RC, Salek RM, Sarkans U, Petryszak R, Keays M, Fahy E, Sud M, Subramaniam S, Barbera A, Jiménez RC, Nesvizhskii AI, Sansone SA, Steinbeck C, Lopez R, VizcaÃno JA, Ping P, Hermjakob H. Nat Biotechnol Volume 35 (2017) p.406-409
