Hiroki Asari
Group Leader
European Molecular Biology Laboratory
European Molecular Biology Laboratory
Germany
Biography
PhD 2007, Cold Spring Harbor Laboratory, USA. Postdoctoral research at Harvard University and the California Institute of Technology, USA. Group leader at EMBL since 2016. Joint appointment with the Developmental Biology Unit.
Research Interest
My research will thus focus on the bidirectional interactions between the retina and the brain, and aim to address the following questions: How is retinal visual processing modulated by efferent inputs from the brain under different behavioral states of an animal? How does retinal processing contribute to computation in the successive stages of the afferent visual pathway? A key to address these questions is to clarify a causal relationship, not just correlation, among visual stimuli, behavioral states, and neuronal activities. I will achieve this by using electrophysiological and optogenetic tools in mice. The experimental results will then be integrated to build a quantitative model that better describes retinal circuit functions and visual processing.
Publications
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Nagarah JM, Stowasser A, Parker RL, Asari H, Wagenaar DA. (2015) Optically transparent multi-suction electrode arrays. Front Neurosci 9 doi: 10.3389/fnins.2015.00384
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Teeters JL, Godfrey K, Young R, Dang C, Friedsam C, Wark B, Asari H, Peron S, Li N, Peyrache A, Denisov G, Siegle JH, Olsen SR, Martin C, Chun M, Tripathy S, Blanche TJ, Harris K, Buzsáki G, Koch C, Meister M, Svoboda K, Sommer FT. (2015) Neurodata Without Borders: Creating a Common Data Format for Neurophysiology. Neuron 88(4):629-634. doi: 10.1016/j.neuron.2015.10.025
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Real E, Asari H, Gollisch T, Meister M. (2017) Neural Circuit Inference from Function to Structure. Curr. Biol. 27(2):189-198. doi: 10.1016/j.cub.2016.11.040