James Sharpe
Head of Outstation and Senior Scientist
European Molecular Biology Laboratory
European Molecular Biology Laboratory
Germany
Biography
PhD, 1997, MRC National Institute for Medical Research, London. Postdoctoral research fellow, 1998-2002, MRC Human Genetics Unit, Edinburgh. Group Leader, 2002-2206, MRC Human Genetics Unit, Edinburgh. Group Leader, Centre for Genomic Regulation (CRG), Barcelona, since 2006. Coordinator of Systems Biology Program, CRG, since 2011. Head of EMBL Barcelona since 2017.
Research Interest
-
Publications
-
Ozga AJ, Moalli F, Abe J, Swoger J, Sharpe J, Zehn D, Kreutzfeldt M, Merkler D, Ripoll J, Stein JV. (2016) pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion. J Exp Med 213(12):2811-2829. doi: 10.1084/jem.20160206
-
Jiménez A, Cotterell J, Munteanu A, Sharpe J. (2017) A spectrum of modularity in multi-functional gene circuits. Mol Syst Biol 13(4):925. doi: 10.15252/msb.20167347
-
Ackerknecht M, Gollmer K, Germann P, Ficht X, Abe J, Fukui Y, Swoger J, Ripoll J, Sharpe J, Stein JV. (2017) Antigen Availability and DOCK2-Driven Motility Govern CD4(+) T Cell Interactions with Dendritic Cells In Vivo. J Immunol doi: 10.4049/jimmunol.1601148
