Dr. Bertolt Gust
Professor
Pharmaceutical Biology
University of Tubingen
Germany
Biography
"Prof/Dr Bertolt Gust has received his PhDon Establishment of a method for the generation of fragment specific cDNAs and transcriptional analysis of Streptomyces coelicolor, Department of Genetics, University of Kaiserslautern, Germany during the period of 1995-2000. Currently, he is working as Professor in Tubingen University. His research has included Molecular biological studies on antibiotic biosynthesis in streptomycetes,Translocase I inhibitors,Nucleoside antibiotics,Synthetic Biology. He have authoredAGOS: A Plug-and-Play Method for the Assembly of Artificial Gene Operons into Functional Biosynthetic Gene Clusters research articles/books. "
Research Interest
Molecular biological studies on antibiotic biosynthesis in streptomycetes,Translocase I inhibitors,Nucleoside antibiotics,Synthetic Biology
Publications
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Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, De Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P. Minimum information about a biosynthetic gene cluster. Nature chemical biology. 2015 Sep 1;11(9):625-31.
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Bekiesch P, Franz-Wachtel M, Kulik A, Brocker M, Forchhammer K, Gust B, Apel AK. DNA affinity capturing identifies new regulators of the heterologously expressed novobiocin gene cluster in Streptomyces coelicolor M512. Applied microbiology and biotechnology. 2016 May 1;100(10):4495-509.
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Bauer JS, Hauck N, Christof L, Mehnaz S, Gust B, Gross H. The Systematic Investigation of the Quorum Sensing System of the Biocontrol Strain Pseudomonas chlororaphis subsp. aurantiaca PB-St2 Unveils aurI to Be a Biosynthetic Origin for 3-Oxo-Homoserine Lactones. PloS one. 2016 Nov 18;11(11):e0167002.
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Basitta P, Westrich L, Rösch M, Kulik A, Gust B, Apel AK. AGOS: A Plug-and-Play Method for the Assembly of Artificial Gene Operons into Functional Biosynthetic Gene Clusters. ACS Synthetic Biology. 2017 Feb 20;6(5):817-25.
