Fattorusso Caterina
Professor of Pharmaceutical Chemistry
Department of Pharmacy
University Federico II
Italy
Biography
Born on 26/10/1970 in NAPLES (NA) Qualification: Associate Professor Seniority in the role: 27/12/2004 University Headquarters: Department of Pharmacy - University of NAPLES "Federico II" Positions previously held in the same university or other institution: from 10/10/1997 University Researcher of SALERNO since 01/11/2000 University Researcher of NAPLES University "Federico II" from 27/12/2004 Professor II University of Naples NAPLES "Federico II" 2013 - National Scientific Enforcement for the First Bands in the Concrete Sector 03 / D1 with the following Bibliometric Indicators (2002-2012): Article Number: 52 - Total Quotations (Scopus): 1607 - h index = 26 Bibliographic indicators updated to 2016: Number of articles: 79 - Total number of citations (Scopus): 2133- h index = 30 Information on the scientific and professional path 1993- Degree in Pharmaceutical Chemistry and Technology obtained on July 23, 1993 at the Faculty of Pharmacy of the University of Naples Federico II with 110/110 votes and praise. Thesis title: "Molecular modeling studies on cholecystokinin inhibitors", rapporteur Prof. Carlo Silipo. 1994-1997 Ph.D. in Pharmacy at the Freie Universitat Faculty of Medicine in Berlin and at the Heinrich Heine University Pharmacy Faculty in Duesseldorf, under the supervision of Prof. Hans-Dieter Hoeltje. 1997- Ph.D. in "Pharmaceutical Sciences" obtained on 9 July 1997 at the Faculty of Pharmacy of the University of Naples Federico II. Thesis title: "Construction of active site of Lanosterol 14-alpha-demethylase through molecular modeling techniques". Tutor: prof. Ettore Novellino.
Research Interest
The areas of scientific interest of prof. Factorusso have always covered the molecular simulation of systems of biological interest through computational techniques and, in particular, the investigation of biological drug / target interactions. Through the use of these techniques he has dealt with the development of new potential drugs in many fields of pharmaceutical chemistry through various computational techniques and using both "target-based" and "ligand-based" approaches.
Publications
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M. Perico, S. Parapini, G. Chianese, C. Fattorusso, M. Lombardo, L. Petrizza, A. Quintavalla, F. Rondinelli, N. Basilico, D. Taramelli, C. Trombini, E. Fattorusso, O. Taglialatela-Scafati (2013). Further optimization of placortin pharmacophore: Structurally simple 4-oxymethyl-1,2-dioxanes with promising antimalarial activity. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 70, p. 875-86. doi: 10.1016 / j.ejmech.2013.10.050.
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M. Lombardo, * DP Sonawane, A. Quintavalla, C. Trombini, DD Dhavale, D. Taramelli, Y. Corbett, F. Rondinelli, C. Fattorusso, M. Persico, O. Taglialatela-Scafati (2014 ) . Optimized Synthesis and Antimalarial Activity of 1,2-Dioxane-4-carboxamides. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. Volume 2014, Issue 8, pages 1607-1614; DOI: 10.1002 / ejoc.201301394
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M. Scuotto, M. Persico, MR Bucci, V. Vellecco, N. Borbone, E. Morelli, G. Oliviero, E. Novellino, G. Piccialli, G. Cirino, M. Varra, * C. Fattorusso , * L Mayol. Outstanding effects on the antitrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue (2014). Just Accepted on ORGANIC & BIOMOLECULAR CHEMISTRY. (2014). Accepted Manuscript Number: OB-ART-01-2014-000149.R1.
