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Grieco Paolo

Professor of Pharmaceutical Chemistry
Department of Pharmacy
University Federico II
Italy

Biography

Paolo Grieco graduated in Pharmaceutical Chemistry and Technology at the University of Naples '' Federico II ''. He obtained his doctorate in Pharmaceutical Sciences in 1993, working on solid-phase peptide synthesis. From 1998 to 1999 he was a researcher at the Department of Chemistry and Biochemistry at the University of Arizona, under the supervision of Prof. Victor J. Hruby, working on the development of peptide and peptidomimetic ligands active on melanocortin receptors. In 2001 he was appointed associate professor in Pharmaceutical Chemistry at the University of Naples "Federico II". Since December 2011 he has been a professor in Pharmaceutical Chemistry at the Department of Pharmacy at the University of Naples Federico II. He is the author of more than 170 scientific publications in international journals, focusing mainly on peptide and peptidomimetic chemistry. He is also the author of several patents on the discovery of new molecules as potential therapeutic agents and diagnostic applications. His research activity focuses on the chemistry of peptides, peptidomimetics, small organic molecules such as receptor ligands that include several therapeutic areas including the cardiovascular system and central nervous system. Prof. Paolo Grieco is a member of the Italian Chemical Society, the European Peptide Society and the American Peptide Society. Finally, he is co-founder of the Italian Society of Peptides.

Research Interest

Melanocortinic peptide Peptides and Peptidomimetics Active on the Urotensinergic System Antimicrobial Peptides

Publications

  • Multiple beneficial effects of melanocortin MC4 receptor agonists in experimental neurodegenerative disorders: Therapeutic perspectives

  • Urotensin-II Receptor: A Double Identity Receptor Involved in Vasoconstriction and in the Development of Digestive Tract Cancers and other Tumors

  • Development and Identification of a Novel Anti-HIV-1 Peptide Derived by Modification of the N-Terminal Domain of HIV-1 Integrase

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