Russo Annapina
Biochemist Researcher
Department of Pharmacy
University Federico II
Italy
Biography
2000: Degree in Pharmaceutical Chemistry and Technology, University of Naples "Federico II" 2000 - 2004: Ph.D. in Biochemistry and Medical Biotechnology (XVI cycle) at the Department of Biochemistry and Medical Biotechnology, University of Naples "Federico II" January 2005: Ph.D. in Biochemistry and Medical Biotechnology. PhD thesis: "Asymmetric Distribution of MRNAs for Ribosomal Proteins in the Cytoplasm" 2005: Contractor for a coordinated and continuing collaborative assignment at the Department of Biochemistry and Medical Biotechnology, Naples University "Federico II", for the following activity: "Construction of eukaryotic expression vectors for the analysis of stability and localization of specific mRNAs " 2006 - 2008: Holder of a two-year check for collaboration in research activities at the Department of Biochemistry and Medical Biotechnology, University of Naples "Federico II", for carrying out the following activity: "Post-transcriptional regulation of gene expression of human ribosomal proteins " 2008 - 2009: Renewal of one year's grant for research collaboration (3rd year of check) at the Department of Biochemistry and Medical Biotechnology, University of Naples "Federico II" 2009 - 2010: Renewal of a one year grant for collaboration in research activities (IV year of check) at the Department of Biochemistry and Medical Biotechnology, University of Naples "Federico II" 2010 - 2011: Holder of an annual scholarship at the Department of Biochemistry and Biotechnology of the University of Naples "Federico II", for carrying out the following activity: "Alternative Splicing in Regulating Gene Expression" 2013: Holding a scholarship at the Department of Pharmacy, University of Naples "Federico II", for carrying out the following activity: "RpL3 role in regulation of p21 expression and in response to chemotherapy with 5- FU in human cancer cells " 2013- 2016: Researcher with fixed-term employment relationship, for the duration of three years, pursuant to art. 24 paragraph 3, lett. a) of Law no. 240/2010, for carrying out research, didactics, supplementary teaching and student service - for the BIO / 10 competition field at the Department of Pharmacy, University of Naples "Federico II" 2016 to date: Extension as a Researcher with a fixed-term employment relationship, for the duration of three years, pursuant to art. 24 paragraph 3, lett. a) of Law no. 240/2010, for carrying out research, didactics, supplementary teaching and student service - for the BIO / 10 competition field at the Department of Pharmacy, University of Naples "Federico II" TEACHING ACTIVITY 2012 - 2013: Professor for Integrative Teaching Activities of the Nutrition Physiology and Biochemistry Teaching, Hospitality Pharmacy Specialization School, Department of Pharmacy University of Naples "Federico II" 2014 to present: Biochemistry and Molecular Biology Course, Degree in Scientific Information on Medication and Diagnostic Products, Department of Pharmacy, University of Naples "Federico II" 2014 to Today: Biochemistry Teaching Supplement, Module B, Degree in Pharmacy, Department of Pharmacy, University of Naples "Federico II"
 2015 to date: Holder of the course of Biochemistry of Nutrition, Degree in Nutraceutical Sciences, Department of Pharmacy, University of Naples "Federico II"
Research Interest
P53 gene inactivation in cancer - Ribosomal protein-MDM2-p53 pathway study as goal in cancer therapy - Identification of new resistance mechanisms to chemotherapy independent of p53 - Understanding the molecular mechanisms of antitumor drugs commonly used in clinical treatments - Role of the p53 gene in cancer ribosomal proteins in tumorigenesis, chemotherapy and chemotherapy - Study of the molecular mechanisms responsible for cancer-related inflammatory processes with particular attention to classical inflammatory components such as NFκB - P53-dependent p53 mitochondrial apoptosis study as a mechanism for survival and / or chemotherapy resistance .
Publications
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Role of uL3 in Multidrug Resistance in p53-Mutated Lung Cancer Cells