Filippo Cottiglia

Biography

Since 2002 Assistant professor in Medicinal Chemistry at the Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Cagliari. 2000-2001 Postdoctoral position in the group of Prof. Dr. Otto Sticher, Pharmacognosy and Phytochemistry, Department of Applied BioSciences, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland 1999-2000 Postdoctoral position in the group of Prof. Leonardo Bonsignore at The Chemical Technology Dip. 2000 Specialist in Industrial Pharmacy, University of Pavia, Italy, the only school in Italy that specializes in training experts for managerial places in the pharmaceutical industry. 1998-1999 Awarded post doctoral exchange of study grant at The Department of Pharmaceutical Chemistry. 1995-1997 PhD in "Pharmaceutical Chemistry", University of Cagliari, under the supervision of Prof. Leonardo Bonsignore. Thesis title: "Synthesis and Antimicrobial Activity of Penicillin and Semisynthetic Cephalosporins obtained by Carbon Dioxide Reactions". 1993 Graduated at the "University of Cagliari" in Chemistry and Pharmaceutical Technologies with 110/110 points, summa cum laude.

Research Interest

In the Research Laboratory of Biologically Active Natural and Synthetic Molecules, the following lines of research are pursued: Isolation and clarification of the structure of biologically active secondary metabolites from Sardinian, Indian and marine organisms. Isolation involves bio-directed extraction of the extracts by the use of chromatographic techniques such as TLC, CC, VLC, HPP semipreparative. The structure is elucidated by NMR (1D and 2D), UV, IR, MS spectroscopy. Synthesis and semi-synthesis of analogues of biologically active natural products. HPLC semipreparative enantioseparation of racemic mixtures.