Marcello Carla

Biography

Education: Degree in Physics, University of Florence, Italy, on 29-7-1974 (rating 110/110 and praise) with a thesis "Automatic control of an electrostatic accelerator by a digital computer: design and setup of the working parameters measurement system and its application to nuclear physics experiments. Positions 1975-1976 One year grant at the Institute of Physics of Florence. 1976-1985 Graduated Technician at the Institute of Physical Chemistry of Florence (1983, Department of Chemistry). 1985-present Associate Professor in Experimental Physics at the Department of Florence. Research activity 1976-1985 Application of the digital computer to the development of new instrumentation for the measurement of the physico-chemical properties of polarized liquid-liquid interphases and study of surfactants adsorption / desorption behavior under the action of the interphasal electrical field. 1985-1995 Investigation of the action mechanism of PAI's (Polar / Apolar Inducers) and explanation of their biological effects as a result of their adsorption at the charged surface of the cell membrane. PAI's are heterogeneous compounds endowed with the property to induce differentiation into transformed cell lines. 1995-2000 Development of a new double differential technique for the absolute measurement of the complex dielectric constant of fluids and application to the study of interphasic water in complex fluids. After 2000 Study by impedance spectroscopy of conduction properties of hydration layers on an insulating surface in moist atmosphere. Implementation of a Scanning Electrochemical Microscopy (SECM) technique based on the conduction of a hydration layer on the surface of a cleaved mica sheet and application to imaging of organic macromolecules of biological interest. Use of SECM to study the relaxation kinetics of liquid nanostructures, on a time scale from sec. down to a fraction of one millisec. Implementation of a Scanning Electrochemical Microscopy (SECM) technique based on the conduction of a hydration layer on the surface of a cleaved mica sheet and application to imaging of organic macromolecules of biological interest. Use of SECM to study the relaxation kinetics of liquid nanostructures, on a time scale from sec. down to a fraction of one millisec. Implementation of a Scanning Electrochemical Microscopy (SECM) technique based on the conduction of a hydration layer on the surface of a cleaved mica sheet and application to imaging of organic macromolecules of biological interest. Use of SECM to study the relaxation kinetics of liquid nanostructures, on a time scale from sec. down to a fraction of one millisec.

Research Interest

Research 1976-1985 Application of the digital computer to the development of innovative instrumentation for the measurement of chemical-physical properties of liquid-liquid polarized interfaces; study of adsorption / desorption mechanisms of surfactants under the ' action of the interfacial electric field. 1985-1995 Study of PAI (Polar / Apolar Induction) Mechanism of Action and interpretation of their biological efficacy as a result of the adsorption properties of the cell membrane polarized surface. Pai are heterogeneous chemical compounds with the ability to induce certain cell lines undergoing neoplastic transformation to differentiate. 1995-2000 Development of a new double-differential technique for absolute complex dielectric fluid fluids and application to the study of interfacial water in complex fluids. Since 2000, the study is based on spectroscopy of conduction impedance in layers of hydration on insulating surfaces. Development of an Electrochemical Scan Microscope (SECM) system based on the conduction of a moisturizing layer on the surface of a mica foam sheet and its application to the study of organic macromolecules of biological interest. Application of SECM to the study of kinetic relaxation in liquid nanostructures of mica water at times from sec. to the fraction of msec.