Cavestro Giulia Martina

Biography

EDUCATION AND TRAINING 2001-2005 Research Physiopathology in Hepato-Digestive at the University of Parma, discussing the thesis "Role of gene mutations of cytic trypsinogen and its inhibitor, citocheratine 8 and CFTR in the pathogenesis of chronic pancreatitis" 1996-2000 Specialization in Gastroenterology in the year 2000 at the University of Parma, discussing the thesis "HLA Association Study, Necrosa Tumor Factor α (TNFα), TAP Transmitters and CFTR in the course of Prestigious Sclerosing Colangitis (CSP) ". 1990-1996 Degree in Medicine and Surgery at the University of Padua, discussing the thesis entitled: "Experimental evidence of a Na + / H + exchanger in the basolateral and apical plasma membrane of the biliary epithelial cells of the rat". PROFESSIONAL EXPERIENCES OUTSIDE 1995-1997 Yale University, Department of Internal Medicine, Department of Digestive Diseases, New Haven, CT, USA for research activities by applying molecular biology methodologies to the study of biliary secretion. UNIVERSITY CURRICULUM From March 2013 University Researcher confirmed on 30/12/2005 for MED-12 (Gastroenterology) disciplinary science at the Faculty of Medicine and Surgery of San Raffaele Health University, Milan. From January 2011 to February 2013 Full-time Visiting Professor at San Raffaele University of Health and Welfare Gastroenterology and Digestive Endoscopy Operations Unit to carry out research and research in pancreatic surgery and refine endoscopy techniques. This activity was carried out on extraordinary leave by the University of Parma for reasons of study pursuant to art. 8 of Law 349/58 and the combined provisions of art. 34, 1st paragraph of Presidential Decree 382/80. From 2002 to 2013 University Researcher confirmed in December 2005 for the disciplinary field MED-12 (Gastroenterology) at the Faculty of Medicine and Surgery of the University of Parma, Department of Clinical Sciences, Department of Gastroenterology. 2000-2002 Scientific research funded by the University of Parma for the Feliciani-Ferretti legacy, for the research project: "Role of the system of higher compatibility (MHC)" and the mutations of the CFTR channel in genetic predisposition to primitive sclerosing colangitis and idiopathic chronic pancreatitis. " 1997-2001 University doctor in Gastroenterological training with care and care at the Semeiotica Institute, Chair of Gastroenterology of the University of Parma.

Research Interest

Responsible for the "biobanks project for the study of association between environmental and genetic factors in inflammatory, functional and gastroenterological neoplastic diseases" Since 2011, date of approval of protocol BIOGASTRO / 2011 by the Ethics Committee of the Fondazione Centro San Raffaele of Monte Tabor Scientific Institute San Raffaele Hospital, Milan. About 900 patients have been enrolled in this project. This biobank has produced collaboration with international groups listed below. Head of Gastroenterology Molecular Research Laboratory 2001-2013 Head of Gastroenterology Research Laboratory at the University of Parma, Department of Clinical Sciences, using molecular biology methods (amplification, sequencing, mutagenic analysis) applied to gastroenterological pathologies such as acute pancreatitis, chronic pancreatitis, pancreatic cancer, chronic intestinal inflammatory diseases. International Collaborations: - Pan-European Working Group. Project: Genetic Risk Contribution to Alcoholic Chronic Pancreatitis, Pan-European Working Group. - PANcreatic Disease ReseArch (PANDoRA) Consortium. - Boston University School of Medicine and Boston Medical Center, Gastroenterology Unit, USA (Satish K. Singh). Projects: Clinical and molecular characteristics of inflammatory pancreatic diseases; Spectroscopic assessment of mucosal pathologies at gastrointestinal endoscopy; Detection of field effect of carcinogenesis of gastrointestinal cancer using elastic scattering spectroscopy. - Arizona State University, School of Life Sciences, Arizona Arizona State University, Douglas F. Lake. Project: Identification of circulating molecular markers for non-invasive diagnosis of GI cancer - Pädiatrische Ernährungsmedizin , University of Leipzig, Leipzig, Germany (Jonas Rosendahl) - ARC-NET Research Center (University of Leipzig, Heiko Witt) - Department of Gastroenterology and Hepatology for Applied Research on Cancer Department of Pathology and Diagnostics, University Hospital of Verona (Aldo Scarpa) - Genomic Epidemiology Group German Cancer Research Center, Heidelberg, Germany (Canzian Federico). Project: Participation in the genome-wide association study on pancreatic cancer cancer risk of the Pancreatic Cancer Case Control Consortium (PanC4). - Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-v.-Guericke-University, Magdeburg (Peter Malfertheiner) Participation in Ministerial Projects: 1998-1999: "Primitive Sclerosing Colangitis: pathogenetic role of cystic fibrosis genes mutations" 1999-2000: "Primitive Sclerosing Colangitis and Association with TNFα -308 Polymorphism" 2000-2001: "Pancreatitis chronic Idiopathic and association with specific HLA antigens (A, B, DR1) and TNFα -308 polymorphism. " 2001-2002:" Genetic susceptibility factors in the pathogenesis of chronic pancreatitis. " 2003-2004: Metabolism of inhibitor drugs proton gastric pump and CYP2C19 enzyme polymorphism 2004-2005: Role of Keratine 8 gene mutations and TNF-α gene polymorphism in genetic predisposition to chronic intestinal inflammatory diseases Participation in national inter-university research projects (Ministry of Education's funding): 1998-2000 (Biennial): Cholestasis in humans and experimental models. Cellular and molecular biology of biliary secretion and its alterations as a cause of liver damage and progression of disease. 2000-2002 (Biennale): Cell death, death and proliferation of biliary epithelium in human and experimental cholestasis Participation in Finalized Health Research Projects (Health Ministry Funding): 2004-2006 (Biennial): "Innovative Strategies for Early Diagnosis, Follow-Up and Cancer Therapy of the Esophagus and Cardias" TEACHING ACTIVITY San Raffaele Health University, Faculty of Medicine and Surgery: - From the Academic Year 2013-2014: Holder of the "Gastroenterology" course, Degree Course in Dentistry and Dental Prosthesis (CLMOPD) San Raffaele Vita-Salute University, Milan - From the Academic Year 2011-2012 Holder of the "Gastroenterology" course, Degree in Dental Hygiene (CLID270) Vita-Salute San Raffaele University, Milan - Academic Year 2011-2012 Trust in "Digestive Disease System" in the International Degree Program MD, San Raffaele University, Vita-Salute, Milan Official Teaching of Digestive Diseases for Doctoral Programs (Ph.D) at the University of Florence, Faculty of Medicine and Surgery: - From the Academic Year 2013-2014: Doctoral Program in Biomedical Sciences - Science physiological and nutritional. Official Teaching of Digestive Diseases for Doctoral Programs (Ph.D) at the University of Parma, Faculty of Medicine and Surgery: - From the Academic Year 2008-2009: PhD in Epilebiology- pancreatic and advanced hepato-digestive pathophysiology, University of Parma, Faculty of Medicine and Surgery. Teaching assignments at the specialty schools of the University of Parma, Faculty of Medicine and Surgery: * Specialization Schools - Specialization Degree in General Surgery "Gastroenterology", from 2010/2011 to 2012/2013 - School of Specialization in Dermatology and Venereology "Gastroenterology", in 2010/2011 at the AU 2012/2013 - School of Specialization in Endocrinology and Spatial Disease "Gastroenterology", in 2004/2008 at the AU 2012/2013 - Specialization School in Geriatrics "Gastroenterology", in 2008/2009 at 2012/2013 "Aging of gastrointestinal tract and related pathologies", in 2004-2011 at the 2012/2013 "Gastrointestinal Disease", at 2010/2011 at 2012 / 2013 - Gastroenterology Specialist School "Gastroenterology", in 2008/2009 at the 2012/2013 "Physiopathology of Pancreatic Diseases", 2003/2008 at the AU 2012/2013 - School Nutrition Specialization in Nutrition Science " Gastroenterology and Nutrition in Adult ", in 2006/2007 at the 2012/2013 " Clinical Nutrition of the Aging Age ", in 2007/2008 at the 2012/2013 " Adult Nutrition Clinic ", aa 2007/2008 all 'aa 2012/2013 * Teaching assignments at the Specialized Degree Course in Medicine and Surgery: - Integrated Course "Digestive and Endocrine System Diseases" Didactic Form of Pancreatic Physiopathology aa.aa 2004-2009 to 2012/2013 - Integrated Course " digestive and endocrine system "Clinical module and bilio-pancreatic disease therapy aa.aa 2002-2004 aa 2012/2013 - Gastroenterology (internship) (0.5 CFU) (CI Digestive Diseases)", 2009/2010 ay 2012/2013 - Gastroenterology (Internship) (1 CFU) (CI Digestive diseases) ", aA to aA 2009/2010 2012/2013 - Gastroenterology (Internship) (Mod. 2) (1.5 CFU) (CI Digestive and Endocrine Diseases) ", to 2008-2009 at the AU 2012/2013 * Official Teaching of Digestive Diseases for Doctoral Programs (Ph.D) at the University of Parma, Faculty of Medicine and Surgery: - 2006-2007: Doctoral Program in Hepatic-Digestive Physiopathology, Faculty of Medicine and Surgery, University of Parma (XI, XII cycle). * Teaching elective teaching activity (ADE) for the Bachelor in Medicine and Surgery at the University of Parma: - Clinical approach to the patient suffering from gastroenterological illnesses. - Ultrasound and Endoscopy in Gastroenterology. - Genetic alterations associated with diseases of the digestive system. - Gastrointestinal pathology: from clinic to microscope. - Gastroenterology seminars * Rapporteur for 10 Thesis in Medicine and Surgery * Tutor of 4 PhD theses in Medicine and Surgery ASSISTANCE ACTIVITY Since March 2013 University Researcher Confirmed in agreement with the San Raffaele Hospital (senior) case manager for the MED-12 (Gastroenterology) disciplinary sector at the Gastroenterology Comprehensive Unit. Since January 2011, the activity of diagnostic and operative endoscopy of high (1000 EGDS / year) and low digestive tract (1000 Pancolonscopes / year) at the complex UO of Digestive Endoscopy at San Raffaele Hospital in Milan. Since January 2011, clinical activity at the specialized pancreatic surgery (acute pancreatitis, chronic pancreatitis), consisting of six / eight weekly visits at the UO Digestive Endoscopy of San Raffaele Hospital in Milan. From 2007 to 2011: Head of Expert Case Manager (Senior) at the Comprehensive Unit of Gastroenterology and Digestive Endoscopy of the Parma Hospital-University Company, performing the following duties: Head of Department of Gastroenterology (22 beds of ordinary hospital) Clinical activity at the general outpatient clinic of Gastroenterology (direct access to the field medicine). Diagnostic and operating endoscopy sessions of high (1000 EGDS / year) and low digestive tract (1000 Pancolonscopes / year). Clinical activity at the specialized outpatient clinic for pancreatic disorders (acute pancreatitis, chronic pancreatitis), consisting of six weekly visits. 2002-2005: Case Manager Medical Manager at the Comprehensive Unit of Gastroenterology and Digestive Endoscopy of the Azienda Ospedaliera Universitaria di Parma MEMBER OF SCIENTIFIC SOCIETIES / RESEARCH GROUPS - Italian Society of Gastroenterology (SIGE) since 1997; since 2001 Member of the Scientific Committee - American Pancreatic Association (APA) since 2007 - European Pancreatic Association (EPC) since 2010 - Italian Association Studio Pancreas (AISP) since 2001 - Interdisciplinary Group Studio Colelitiasi (GISCo.) since 2000 - Interdisciplinary Group on Gastric Epithelial Dysplasia (IGGED) since 2000 AWARD FOR SCIENTIFIC ACTIVITIES - VI Congress of the National Federation of Digestive Diseases Awards for the study: "Contribution of the MHC gene genes of CFTR mutations to genetic predisposition to primitive sclerosing colangitis". - Grant Award, presented by the European Association of Gastroenterology at the United European Gastroenterology Week (UEGW) for the study: "Keratin 8 mutations in patients with chronic pancreatitis". - Grant award awarded by the European Association of Gastroenterology at the 2006 UEGW Congress as Best Work (Connections between genetics and clinical data in the setting of acute, acute recurrent and chronic pancreatitis). - Award as Best Work Congress of the American Pancreatic Association Chicago November 2006 (Connections between genetics and clinical data in acute, acute recurrent and chronic pancreatitis). - Sixth Congress of the National Federation of Digestive Diseases Awards for the Study: "Contribution of MHC gene genes of CFTR mutations to genetic predisposition to primitive sclerosing colangitis". CONGEDI - Leave for Maternity (Law 30/12/71 no 1204) 24/04/2007 to 24/09/2007 - Leave for Maternity (Law 30/12/71 no 1204) from 20/11/2009 to 16/01/2011 - Extraordinary leave for reasons of study pursuant to art. 8 of Law 349/58 and the combined provisions of art. 34, 1st paragraph of Presidential Decree 382/80, for carrying out studies, research and development of endoscopy techniques at the San Raffaele Institute in Milan, Life and Health University, Gastroenterology and Digestive Endoscopy Service since 17/01 / 2011 to 16/01/2013