Consul Philip

Biography

Career 2017-present: Researcher at the Faculty of Medicine and Surgery of San Raffaele Health Life University. Main research topic: Development of innovative diagnostic tools and their technological translation in the cardiovascular clinical field. 2010-2016: Research Assistant at the Department of Electronics, Information and Bioengineering at the Politecnico di Milano. Main research topic: Design of engineered (bioreactors) and miniaturized dynamic systems (microfluidic platforms) for the conditioning and functionalization of cellular constructs for the regeneration of organs and tissues. 2014: Research project: "Optimizing the performance of a heat exchanger for cardiopulmonary by-pass". SORIN Group Italy 2013: Visting PhD Student at Biofluids Laboratory (Bluestein Lab), Biofluids Research Group, Biomedical Engineering Engineer, Stony Brook University, NY, USA. (). 2010: Ph.D. in Biomedical Engineering at the Department of Mechanical Engineering - Division of Bioengineering - of the Politecnico di Torino. Ph.D. thesis: Computational modeling and Bionanotechnology: a multidisciplinary approach to the design of tissue engineering applications. (Tutor: Prof. Alberto Maria Montevecchi, Prof. Alberto Redaelli, Prof. Umberto Morbiducci). 2009: Visting PhD Student at the Biomacromolecole Laboratory of the University of Chemistry at Alma Mater Studiorum University of Bologna, Bologna, IT (Responsible: Prof. ML Focarete). 2008: Visting PhD Student at the Faculties of Physics of the Ciências and Technology of the Nova de Lisboa University, Lisbon, PT (Responsible: Prof. J Silva). Master of Level II "Design Elements of Micro- and Nanotechnologies for Bioartificial Systems". Polytechnic of Turin, Dip. Of Mechanics. 2006: Master's Degree in Biomedical Engineering. Dept. of Bioengineering, Polytechnic of Milan. Thesis title: Integrated computational model and experimental analysis for the study of transport phenomena in a capillary fiber bioreactor for artificial liver. (Tutor: Prof. Alberto Redaelli, Prof. Gianfranco Fiore). 2003: I degree in Biomedical Engineering. Dept. of Bioengineering, Polytechnic of Milan. Title of thesis: "Development of software for the analysis of velocity curves related to intracoronary acquisition". (Tutor: Prof. Alberto Redaelli, Prof. Gianfranco Fiore, Thesis in collaboration with Cardio Surgery Department, L. Sacco Hospital, Milan - Dr. M. Lemma).

Research Interest

esearch activity Translational research activities in the cardiovascular clinical field. The main aim of the research is to develop innovative diagnostic tools that can predict and limit the risk of thrombotic and hemorrhagic complications in patients with left ventricular assist devices (LVADs, ExtraCorporeal Membrane Oxygenator, ECMO) . The research is carried out in collaboration with the Department of Intensive Cardiac Surgery and with the Thrombotic Research Unit of the San Raffaele Hospital of Milan (Dr. Federico Pappalardo, Dr. Alberto Zangrillo, Dr. Armando D'Angelo). The research is carried out by combining the use of different methodologies such as: non-invasive diagnostic for the evaluation of ventricular emodynamics (3D TT Echo) Numerical simulation (CFD) for predicting damage to blood cells (platelets) induced by mechanical stress (shear-stress) within the circulatory care systems (Platelet Activity State (PAS) assay, Thrombin Generation Test (TGT)) for the in vivo characterization of platelet activation phenomena and the effectiveness of pharmacological therapy.