Tomoko Yamamoto
Professor
Division of Clinical Research
Chiba University
Japan
Biography
Professor in Medical Mycology Research Center, Chiba University, Research Projects are Project for Host Response Network of Bacterial Infection and Specialities in Bacteriology, Infection Biology.
Research Interest
Dissecting the molecular mechanisms of systemic infection and persistent infection by facultative intracellular bacteria through the study of Salmonella-host interplay: We focus on the Salmonella effectors, which we have identified through a meta-analytic approach to the accurate prediction of effectors, to elucidate the dynamic interplay with their host targets and bacterial strategies for withstanding the host innate- and acquired-immune systems.
Publications
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Matsui H, Fukiya S, Kodama-Akaboshi C, Eguchi M, Yamamoto T. Mouse models for assessing the cross-protective efficacy of oral non-typhoidal Salmonella vaccine candidates harbouring in-frame deletions of the ATP-dependent protease lon and other genes. J Med Microbiol. 64:295-302 (2015).
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Takaya A, Kimura A, Sato Y, Ishiwada N, Watanabe M, Matsui M, Shibayama K, Yamamoto T. Molecular characterization of linezolid-resistant coagulase-negative Staphylococcus isolates in Japan. J. Atimicrob. Chemother. 70(3):658-63 (2015).
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Shoji T, Takaya A, Sato Y, Kimura S, Suzuki T, Yamamoto T. RlmCD-mediated U747 methylation promotes efficient G748 methylation by methyltransferase RlmAâ…¡ in 23S rRNA in Streptococcus pneumoniae; interplay between two rRNA methylations responsible for telithromycin susceptibility. Nucleic Acids Research, 43(18):8964-72 (2015).
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Ishiwada N, Takaya A, Kimura A, Watanabe M, Hino M, Ochiai H, Matsui M, Shibayama K, Yamamoto T. Linezolid-resistant Staphylococcus epidermidis associated with long-term, repeated linezolid use in a pediatric patient. J Infect Chemother ; 22(3):187-90, 2016.
