Eiichi N Kodama
Professor
Laboratory of Infectious Disease
Tohoku University
Japan
Biography
Dr. Eiichi N Kodama is Professor at Laboratory of Infectious Disease, Tohoku University. His research theme are Development of antiviral agents, Mechanism of resistance.
Research Interest
virus, rational drug design, resistance, mutation, Drug development, Chemical biology, induction of resistance, biosafety
Publications
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Michailidis, E., Marchand, B., Kodama, E. N., Singh, K., Matsuoka, M., Kirby, K. A., ... & Mitsuya, H. (2009). Mechanism of inhibition of HIV-1 reverse transcriptase by 4′-ethynyl-2-fluoro-2′-deoxyadenosine triphosphate, a translocation-defective reverse transcriptase inhibitor. Journal of Biological Chemistry, 284(51), 35681-35691.
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Hachiya, A., Kodama, E. N., Sarafianos, S. G., Schuckmann, M. M., Sakagami, Y., Matsuoka, M., ... & Oka, S. (2008). Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors. Journal of virology, 82(7), 3261-3270.
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Kodama, E. N., McCaffrey, R. P., Yusa, K., & Mitsuya, H. (2000). Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotidyl transferase-positive (TdT+) leukemic cells. Biochemical pharmacology, 59(3), 273-281.
