Goh, Eyleen
Assistant Professor
Neuroscience & Behavioural Disorders
Duke-NUS Graduate Medical School
Singapore
Biography
Asst professor Eyleen Goh is a senior research scientist at the National Neuroscience Institute and an assistant professor with the Duke-NUS Medical School in Singapore. Her research laboratory aims to understand the fundamentals of brain development and functions, and to search for possible intervention strategies for neurodevelopmental and neurodengenerative disorders. Besides the usual pharmaceutical approach, they are also exploring nutraceutical approach for the treatment of these brain disorders. Using cell cultures, animal models and human patient-derived cells, the lab is investigating the effects of micronutrients on neuronal development, circuitry and cognitive functions, to understand how micronutrients or the transport of these micronutrients affect brain functions and to determine if micronutrients can be used as treatment for neurological disorders.
Research Interest
Neuroregeneration in the developing and adult central nervous system (CNS),Nutrition in brain development and neurodevelopmental disorders (Macrocephaly and Rett Syndrome),Nutrition in brain development and neurodevelopmental disorders (Macrocephaly and Rett Syndrome).
Publications
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Tan KK, Tann JY, Sathe S, Goh SH, Ma DL, Goh EL, Yim EK (2015) Enhanced Differentiation of Neural Progenitor Cells into Neurons of the Mesencephalic Dopaminergic Subtype on Topographical Patterns. Biomaterials. 43: 32-43
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Ma DL, Yoon S, Yang C, Marcy G, Zhao N, Leong WY, Ganapathy V, Han J, Van Dongen AMJ, Ming G-L, Hsu K, Augustine GJ and Goh EL (2015) Rescue of MeCP2 dysfunction-induced defects in newborn neurons by modulating GABA signaling. Neurotherapeutics, 10.1007/s13311-015-0343-0