Austin Elliott
Lecturer
Life Sciences
University of Manchester
United Kingdom
Biography
I originally came to Manchester in the late 80s as a specialist in biomedical NMR spectroscopy NMR was very fashionable at the time in metabolic biochemistry and physiology. The special power of NMR was that it allowed minute-by-minute measurements of things like intracellular pH and ATP levels in intact living tissues. I had first come across NMR as an undergraduate studying chemistry and biochemistry, and then did a Ph.D. applying NMR to skeletal and cardiac muscle. After coming to Manchester I switched to using fluorescent probes to make non-invasive measurements of intracellular ion levels.
Research Interest
Calcium signalling, divalent cation transport and stimulus-response coupling in mammalian cells
Publications
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Best, L., Elliott, A. C., & Brown, P. D. (2007). Curcumin induces electrical activity in rat pancreatic β-cells by activating the volume-regulated anion channel. Biochemical Pharmacology, 73(11), 1768-1775.
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Baggaley, E. M., Elliott, A. C., & Bruce, J. I. E. (2008). Oxidant-induced inhibition of the plasma membrane Ca2+-ATPase in pancreatic acinar cells: Role of the mitochondria. American Journal of Physiology: Cell Physiology, 295(5), C1247-C1260.
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Mankad, P., James, A., Siriwardena, A. K., Elliott, A. C., & Bruce, J. I. E. (2012). Insulin protects pancreatic acinar cells from cytosolic calcium overload and inhibition of plasma membrane calcium pump.The Journal of biological chemistry, 287(3), 1823-1836.
