John S Tregoning
Researcher
Faculty of Medicine
National Heart Lung Institute
United Kingdom
Biography
My group aims to: 1. Develop and test vaccines for respiratory infections, particularly for children. 2. Understand why some individuals get more severe disease following respiratory infection. Mouse In vivo imaging of luciferase in mice To achieve these aims, we have developed a range of in vivo and in vitro models of infection and vaccination in early life, including RSV, Influenza, Pseudomonas aeruginosa, Staphylococcus aureus and non-typeable Haemophilus influenzae (ntHi). I did my Post-Doc at Imperial College with Prof Peter Openshaw, working on RSV and for my PhD I worked on the development of a tetanus vaccine expressed in the chloroplasts of transgenic tobacco plants in the labs of Professors Peter Nixon and Gordon Dougan, also at Imperial College. I studied genetics at Downing College, Univeristy of Cambridge.
Research Interest
genetics
Publications
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Gill SK, Hui K, Farne H, et al., 2016, Increased airway glucose increases airway bacterial load in hyperglycaemia, Scientific Reports, Vol:6, ISSN:2045-2322
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Kinnear E, Lambert L, McDonald JU, et al., 2017, Airway T cells protect against RSV infection in the absence of antibody, Mucosal Immunology, ISSN:1933-0219
