Dr Michael Hall
Senior Lecturer
Natural and Environmental Sciences
New Castle University
United Kingdom
Biography
After finishing my DPhil with Dr. Jeremy Robertson (Oxford) entitled "Silicon Tethered Ene and Allyl Transfer Reactions", I moved to Dublin for a postdoctoral position with Dr. Donal O'Shea (UCD) where I worked on the synthesis of switchable photodynamic therapy agents. I then moved to Paris to work with Professor Janine Cossy and Dr Christophe Meyer (ESPCI) on the total synthesis of Phoslactomycin. I subsequently was appointed as a Lecturer in 2007 and then Senior Lecturer in Organic Chemistry in 2016 at Newcastle University. Qualifications DPhil, Linacre College, Oxford, 2003 MChem, Brasenose College, Oxford, 1999 Previous Positions CNRS Postdoctoral Research Fellow, ESPCI, Paris, 2006 Postdoctoral Research Assistant, CSCB, University College Dublin, 2003-2005 Esteem Indicators Associate Editor - RSC Advances
Research Interest
Synthetic organic chemistry: Natural Products, Bioactive molecules, Microwave Chemistry Current Work Current work is divided into three research areas; isolation, characterisation and synthesis of biologically active natural products, new synthetic methodology based on multicomponent "one pot" reactions and the development of new fluorophores for application in bioimaging and sensing.
Publications
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Baksh A, Kepplinger B, Isah H, Probert MR, Clegg W, Wills C, Goodfellow M, Errington J, Allenby N, Hall MJ. Production of 17-O-demethyl-geldanamycin, a cytotoxic ansamycin polyketide, by Streptomyces hygroscopicus DEM20745. Natural Product Research 2017, 31(16), 1895-1900.
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Alnoman RB, Rihn S, OConnor DC, Black FA, Costello B, Waddell PG, Clegg W, Peacock RD, Herrebout W, Knight JG, Hall MJ. Circularly Polarized Luminescence from Helically Chiral N,N,O,O-Boron Chelated Dipyrromethenes. Chemistry - A European Journal 2016, 22(1), 93-96.
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Tyler A, Sejzi HM, Morton S, Waddell PG, Wills C, McFarlane W, Gray J, Goodfellow M, Errington J, Allenby N, Zenkin N, Hall MJ. Structural Reassignment and Absolute Stereochemistry of Madurastatin C1 (MBJ-0034) and the Related Aziridine Siderophores: Madurastatins A1, B1 and MBJ-0035. Journal of Natural Products 2017, 80(5), 1558–1562.
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Cowell J, Buck M, Essa AH, Clarke R, Vollmer W, Vollmer D, Hilkens CM, Isaacs JD, Hall MJ, Gray J. Traceless-Cleavage of Protein-Biotin Conjugates Under Biologically-Compatible Conditions. ChemBioChem 2017, epub ahead of print.
