Holly Janes
Associate Professor
Biostatistics
Fred Hutchinson Cancer Rearch Center
United States of America
Biography
Holly Janes has completed her PhD in Biostatistics at University of Washington and MS at University of Massachusetts
Research Interest
Analysis of vaccine-induced immune responses Design and analysis efficacy trials Evaluation of biomarkers for disease diagnosis/screening, risk prediction and treatment selection
Publications
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Hammer SM, Sobieszczyk ME, Janes H, Karuna ST, Mulligan MJ, Grove D, Koblin BA, Buchbinder SP, Keefer MC, Tomaras GD, Frahm N, Hural J, Anude C, Graham BS, Enama ME, Adams E, DeJesus E, Novak RM, Frank I, Bentley C, Ramirez S, Fu R, Koup RA, Mascola JR, Nabel GJ, Montefiori DC, Kublin J, McElrath MJ, Corey L, Gilbert PB, HVTN 505 Study Team. Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine. N Engl J Med. 2013;369(22):2083-92. PMCID: 4030634.
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Kang C, Janes H, Huang Y. Combining biomarkers to optimize patient treatment recommendations. Biometrics. 2014;70(3):695-707. PMCID: 4248022.
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Janes H, Gilbert P, Buchbinder S, Kublin J, Sobieszczyk ME, Hammer SM. In Pursuit of an HIV Vaccine: Designing Efficacy Trials in the Context of Partially Effective Non-Vaccine Prevention Modalities. AIDS research and human retroviruses. 2013;29(11):1513-23. PMCID: 3809388.
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Janes H, Pepe MS, Bossuyt PM, Barlow WE. Measuring the performance of markers for guiding treatment decisions. Ann Intern Med. 2011;154(4):253-9. PMCID: 3085402.
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Janes H, Pepe MS. Matching in studies of classification accuracy: Implications for analysis, efficiency, and assessment of incremental value. Biometrics. 2008;64(1):1-9.
