Courtney L. Scaife
Professor
Department of Oncological Sciences
Huntsman Cancer Institute
United States of America
Biography
Dr. Courtney Scaife is a Professor of Surgery at the University of Utah who specializes in translational pancreas cancer research and surgical oncology clinical outcomes research. She is an investigator at the Huntsman Cancer Insitute and a member of the Experimental Therapeutics Progarm. Dr. Scaife’s clinical outcomes projects target patient care effectiveness with cost efficiency in general surgical oncology. Dr. Scaife’s translational pancreas cancer research concentrates on pancreatic adenocarcinoma, tumor and stroma interaction. Dr Scaife collaborates as co-Principle Investigator on many projects with the Ph.D.’s in the department of surgery research lab. Their primary interest lies in the understanding of metastases through cellular signaling control for migration and invasion. They also have several collaborations with investigators in the main campus basic science departments and some external collaborations with drug research companies. She has received numerous institutional and industry research support grants through these collaborations. Dr. Scaife has mentored numerous residents and students in her research lab.
Research Interest
Pancreatic Cancer Pancreatic Neoplasms Genotype Carcinoma, Islet Cell Cell Line, Tumor Clinical Outcomes Stromal Cells
Publications
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Martin P, Noonan S, Mullen MP, Scaife C, Tosetto M, Nolan B, Wynne K, Hyland J, Sheahan K, Elia G, ODonoghue D, Fennelly D, OSullivan J (2014). Predicting response to vascular endothelial growth factor inhibitor and chemotherapy in metastatic colorectal cancer. BMC Cancer, 14, 887.
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Benson AB 3rd, DAngelica MI, Abrams TA, Are C, Bloomston PM, Chang DT, Clary BM, Covey AM, Ensminger WD, Iyer R, Kelley RK, Linehan D, Malafa MP, Meranze SG, Park JO, Pawlik T, Posey JA, Scaife C, Schefter T, Sigurdson ER, Tian GG, Vauthey JN, Venook AP, Yen Y, Zhu AX, Hoffmann KG, McMillian NR, Sundar H (2014). Hepatobiliary cancers, version 2.2014. J Natl Compr Canc Netw, 12(8), 1152-82.
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Shen Y, Zificsak CA, Shea JE, Lao X, Bollt O, Li X, Lisko JG, Theroff JP, Scaife CL, Ator MA, Ruggeri BA, Dorsey BD, Kuwada SK (2015). Design, synthesis, and biological evaluation of sulfonyl acrylonitriles as novel inhibitors of cancer metastasis and spread. J Med Chem, 58(3), 1140-58.