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Stuart D. Critz

Professor
Osteopathic Medicine
Lake Erie College of Osteopathic Medicine
United States of America

Biography

Dr. Critz received a Bachelors degree from the University of Massachusetts, a Masters degree from Northeastern University, and a Doctoral degree from the University of Texas Medical School at Houston. After postdoctoral training, Dr. Critz taught at the University of South Alabama College of Medicine for 13 years. His primary teaching activities involved neuro-anatomy, cardiovascular physiology and signal transduction. He was active in research in the field of cardiovascular physiology and his efforts have helped to identify important cellular mechanisms that enable heart tissues to resist infarction during periods of ischemia. Dr. Critz joined the faculty of LECOM Bradenton in 2007. He is active in the Problem-based Learning Pathway in the medical school and teaches anatomy and physiology to pharmacy students. He is active in research and is currently investigating the role of adenosine 2b receptors in cardiomyocytes. The long term objective of this research is to identify A2b receptor agonists for development as therapeutics to prevent infarction in victims of a heart attack.

Research Interest

His research focused on neuroscience, ion channel regulation and signal transduction. He received postdoctoral training in neuroscience and signal transduction in the Department of Neurobiology and Anatomy at the University of Texas Medical School- Houston and in the Department of Molecular Physiology and Biophysics at Baylor College of Medicine

Publications

  • Zimmer, W.E., Zhao, Y., Sikorski, A., Critz, S.D., Sangerman, J., Elferink, L.A., Xu, S., Goodman, S.R. (2000) The domain of brain b-spectrin responsible for synaptic vesicle association is essential for synaptic transmission. Brain Res.881:18-27.

  • Pain, T., Yang. X., Critz, S.D., Yue, Y., Nakano, A., Liu, G.S., Heusch, G., Cohen, M.V., Downey, J.M. (2000) Opening of mitochondrial KATP channels triggers the preconditioned state by generating free radicals. Circ. Res. 87:460-466.

  • Nakano, A., Baines, C.P., Kim, S.O., Pelech, S.L., Downey, J.M., Cohen, M.V., Critz, S.D. (2000) Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: evidence for involvement of p38 MAPK. Circ. Res.86:144-151.

  • Sikorski, A.F., Sangerman, J., Goodman, S.R., Critz, S.D. (2000) Spectrin (bSpIIS1) is an essential component of synaptic transmission. Brain Res. 852:161-166.

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