Laufey Amundadottir
Senior Investigator
Division of Cancer Epidemiology & Genetics, Laboratory of Tr
National Cancer Institute
United States of America
Biography
Dr. Amundadottir received a Ph.D. in cell biology in 1995 from Georgetown University in Washington, D.C. She conducted her postdoctoral training with Dr. Phil Leder in the Department of Genetics at Harvard Medical School in Boston, Massachusetts, then joined deCODE Genetics in Iceland in 1998 as the head of the Division of Cancer Genetics, where she led genome-wide linkage and association efforts in various cancers. Dr. Amundadottir joined the NCI in 2007 as a senior scientist and became a tenure-track investigator in the Laboratory of Translational Genomics in 2008. She was awarded scientific tenure by the NIH and promoted to senior investigator in 2017. Her work focuses on genome-wide association studies (GWAS) and other gene mapping approaches to identify germline variants associated with risk of pancreatic cancer and the functional approaches required to understand the biological mechanisms by which they influence risk of pancreatic cancer.
Research Interest
Gene Mapping in Pancreatic Cancer; Functional Characterization of Pancreatic Cancer Risk Loci
Publications
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Bao Y, Prescott J, Yuan C, Zhang M, Kraft P, Babic A, Morales-Oyarvide V, Qian ZR, Buring JE, Cochrane BB, Gaziano JM. Leucocyte telomere length, genetic variants at the TERT gene region and risk of pancreatic cancer. Gut. 2016 Oct 21:gutjnl-2016.
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Zhang M, Lykke-Andersen S, Zhu B, Xiao W, Hoskins JW, Zhang X, Rost LM, Collins I, van de Bunt M, Jia J, Parikh H. Characterising cis-regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues. Gut. 2017 Jun 20:gutjnl-2016.
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Lindström S, Finucane H, Bulik-Sullivan B, Schumacher FR, Amos CI, Hung RJ, Rand K, Gruber SB, Conti D, Permuth JB, Lin HY. Quantifying the genetic correlation between multiple cancer types. Cancer Epidemiology and Prevention Biomarkers. 2017 Jan 1:cebp-0211.
