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Sharon A. Savage

Branch Chief and Senior Investigator
Division of Cancer Epidemiology & Genetics, Clinical Genetic
National Cancer Institute
United States of America

Biography

Dr. Savage joined the Clinical Genetics Branch, DCEG, NCI in 2006 as a tenure-track investigator. She was awarded scientific tenure by the NIH and appointed senior investigator in 2012. In 2013, she was promoted to Branch Chief. Dr. Savage received her M.D. from the University of Vermont College of Medicine, completed residency training in Pediatrics at Children’s National Medical Center, in Washington DC, and a fellowship in Pediatric Hematology/Oncology at the NCI Pediatric Oncology Branch and Johns Hopkins University. She is board-certified in both Pediatrics and Pediatric Hematology-Oncology. Dr. Savage is an elected member of the American Society for Clinical Investigation. Her current research is focused on the genetic and molecular epidemiology of telomere biology, pediatric cancer etiology, and inherited cancer predisposition syndromes.

Research Interest

Telomere Molecular Epidemiology; Understanding Cancer Etiology - Osteosarcoma; Li-Fraumeni Syndrome

Publications

  • Savage SA, Stewart BJ, Eckert A, Kiley M, Liao JS, Chanock SJ. Genetic variation, nucleotide diversity, and linkage disequilibrium in seven telomere stability genes suggest that these genes may be under constraint. Human mutation. 2005 Oct 1;26(4):343-50.

  • Savage SA, Mirabello L. Using epidemiology and genomics to understand osteosarcoma etiology. Sarcoma. 2011 Mar 8;2011.

  • Mirabello L, Huang WY, Wong JY, Chatterjee N, Reding D, David Crawford E, De Vivo I, Hayes RB, Savage SA. The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer. Aging cell. 2009 Aug 1;8(4):405-13.

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