Michael Lichten
Laboratory of Biochemistry and Molecular Biology
The Center for Cancer Research
United States of America
Biography
Dr. Michael Lichten is a research microbiologist in the Microbial Genetics and Biochemistry Section of this laboratory. He received a Ph.D. in 1982 from M.I.T. (with Maurice S. Fox) and postdoctoral training at Brandeis University (with Dr. James E. Haber). He joined this laboratory as a Senior Staff Fellow in 1987, became a Senior Investigator in 1995, and became a member of the Senior Biomedical Research Service in 2000. He serves on the editorial boards of PLOS Genetics and the Annual Review of Genetics. In 2016, he was elected to membership in the American Academy of Arts and Sciences.
Research Interest
Chromosome Biology, Genetics and Genomics, Molecular Biology and Biochemistry
Publications
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Kaur H, De Muyt A, Lichten M (2015) Top3-Rmi1 DNA single-Strand decatenase is integral to the formation and resolution of meiotic recombination intermediates. Molecular Cell 57: 583-594.
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De Muyt A, Jessop L, Kolar E, Sourirajan A, Chen J, et al. (2012) BLM helicase ortholog Sgs1 is a central regulator of meiotic recombination intermediate metabolism. Mol Cell 46: 43-53.
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Sourirajan A, Lichten M (2008) Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis. Genes Dev. 22: 2627-2632.
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Allers T, Lichten M (2001) Differential timing and control of noncrossover and crossover recombination during meiosis. Cell. 106: 47-58.
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Wu TC, Lichten M (1994) Meiosis-induced double-strand break sites determined by yeast chromatin structure. Science. 263: 5l5-5l8.
