Daniel Bose
Research Fellow
Molecular Biology and Biotechnology
University of Sheffield
United Kingdom
Biography
I started my lab at the Sheffield Institute for Nucleic Acids in MBB during March 2017. Before moving to Sheffield, from 2011 to 2016 I worked as a Postdoctoral Researcher in Prof. Shelley Berger’s lab at the University of Pennsylvania in Philadelphia, and as a Research associate with Prof Xiaodong Zhang and Prof. Dale Wigley at Imperial College London between 2009 and 2011. I completed a PhD in 2008, working with Prof Xiaodong Zhang and Prof Martin Buck at Imperial College. 2017-present: Research Fellow, Sheffield Institute for Nucleic Acids, Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK. 2011-2016: Postdoctoral Research, Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, USA. 2009-2011: Research Associate, Imperial College London, London, UK. 2004-2008: PhD Student, Imperial College London, London, UK.
Research Interest
Gene-regulation; chromatin modification; enhancers; eRNA; non-coding RNA; RNA-binding; epigenetic-enzymes; histone acetylation; CBP/p300; acetyltransferase; cryo-EM; functional genomics; biochemistry.
Publications
-
Klein BJ, Bose D, Baker KJ, Yusoff ZM, Zhang X, Murakami KS. RNA polymerase and transcription elongation factor Spt4/5 complex structure. Proceedings of the National Academy of Sciences. 2011 Jan 11;108(2):546-50.
-
Adelman K, Egan E. Non-coding RNA: More uses for genomic junk. Nature. 2017 Mar 9;543(7644):183-5.
-
Bose DA, Donahue G, Reinberg D, Shiekhattar R, Bonasio R, Berger SL. RNA binding to CBP stimulates histone acetylation and transcription. Cell. 2017 Jan 12;168(1):135-49.
