Patrick Laffy
Research Scientist
Natural Resources
Australian Institute of Marine Science (AIMS)
Australia
Biography
Dr. Patrick Laffy is a Research Scientist: Genomic Bioinformatics. He received my PhD in 2011 in Marine transcriptomics at Flinders University in Adelaide, SA. My PhD focussed on the identification of key enzymes involved in the production of bioactive secondary metabolites from the Australian marine mollusc Dicathais orbita. He analysed transcriptomes from D. orbita, investigating gene expression profiles, and identified key transcripts involved in this secondary metabolite biosynthesis. I also investigated the evolution of the generation of these bioactive compounds within related marine molluscs, and performed recombinant protein expression to characterise an arylsulfatase expressed within D. orbita. He has also had experience working with transgenic plant research, investigating alternative oxidases in the electron transport chain in Arabidopsis thaliana, cereal crop genomics at the Australian Centre for Plant Functional Genomics, and have investigated microsatellite variation in clownfish-hosting anemones from the Great Barrier Reef.
Research Interest
Molecular biology
Publications
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Morrow KM, Bourne DG, Humphrey C, Botté ES, Laffy P, Zaneveld J, Uthicke S, Fabricius KE, Webster NS (2015) Natural volcanic CO2 seeps reveal future trajectories for host-microbial associations in corals and sponges. The ISME Journal 9(4):894-908
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Webster NS, Negri AP, Botté ES, Laffy PW, Flores F, Noonan S, Schmidt C, Uthicke S (2016) Host-associated coral reef microbes respond to the cumulative pressures of ocean warming and ocean acidification. Scientific Reports 6: 19324
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Laffy PW, Wood-Charlson E, Turaev D, Weynberg KD, Botte E, van Oppen MJH, Webster NS, Rattei T (2016) HoloVir: A workflow for investigating the diversity and function of viruses in invertebrate holobionts. Frontiers in Microbiology 7: 822
