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Dr Cheng Xue (helena) Qin

Senior Research Officer
Heart Failure Pharmacology
Baker Heart and Diabetes Institute
Australia

Biography

Dr Chengxue (Helena) Qin has considerable experience in medicinal chemistry and cardiovascular pharmacology through her unique PhD training obtained from University of Melbourne in 2010. Dr Qin's PhD project encompass design, synthesis and profiling an array of novel red wine-flavonols derivatives for treatment of cardiovascular. Excitingly, this group of compounds is now completing phase-II clinical trials in heart attack patients. In 2011, Dr Qin was recruited by Associate Professor Rebecca Ritchie to the Baker Heart and Diabetes Institute to develop novel pharmacological therapies for various cardiovascular disease (e.g. heart attack and diabetes). Her research mainly focuses on formyl peptide receptors, a group of protein involved in the regulation and resolution of inflammation. Dr Qin's studies provided the first evidence that the prototype Cmpd17b is a biased agonist at FPRs, enabling superior cardio-protection over conventional FPR ligands. This cutting-edge platform technology was recently published Nature Communications, and is attracting significant interest from venture capital, big pharma and media. Dr Qin's achievements have also been recognised by numerous highly competitive and prestigious awards including BPS/ASCEPT Outstanding Young Investigator Award; CSANZ Ralph Reader Prize (Basic Science). In addition to traditional academic achievements, Dr Qin has demonstrated a strong passion for commercialisation of research outcomes. She is the Vice-President for the Australia-China Scientist and Entrepreneurs (ACASE). The primary objective of this organisation is to empower scientists to transform technological innovations into tangible social and economic benefits. Under her leadership, ACASE has established solid ties between the Australian and Chinese governments, provided entrepreneurial training and tech-start-up competitions for budding scientists.

Research Interest

Heart Failure Pharmacology

Publications

  • Dr Cheng Xue (Helena) Qin,Cardioprotective potential of annexin-A1 mimetics in myocardial infarction Pharmcol Ther 2015; 148, 47–65.

  • Dr Cheng Xue (Helena) Qin,Adverse vascular remodelling is more sensitive than endothelial dysfunction to hyperglycaemia in diabetic rat mesenteric arteries Pharmacol Res 2016; 111:325–35.

  • Dr Cheng Xue (Helena) Qin,Evidence of ligand-biased signalling at formyl peptide receptor subtypes: potential implications for myocardial ischemia-reperfusion injury Nat Commun 2017:8:14332, pp.1–13.

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