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Dr Hélène Kammoun

Postdoctoral Fellow
Haematopoiesis and Leukocyte Biology
Baker Heart and Diabetes Institute
Australia

Biography

Dr Hélène Kammoun completed her MSc (Honours) in Molecular Biology (Rennes University, France) and her PhD in Physiology and Physiopathology (Pierre and Marie Curie University, Paris, France). During her PhD, funded by a competitive national scholarship, her work demonstrated the importance of the ER stress pathway in the development of hepatic steatosis during obesity. This work novelty led her to present that research in amny national and international conferences and has been extensively cited since then. After her PhD, Dr Kammoun moved to Melbourne to take up a postdoctoral position at the Baker Heart and Diabetes Institute, funded by an NHMRC/INSERM Fellowship. At the Baker Institute, she pursued her work in the diabetes and metabolism field with a new interest towards inflammation. Dr Kammoun contributed to show that the IL6 trans-signalling pathway was a strong signal for recruitment of immune cells to the adipose tissue. She also worked on the testing of some anti-inflammatory compounds for the treatment of type 2 diabetes. In 2016, Dr Kammoun joined the Haematopoiesis and Leukocyte Biology lab. She continues to decipher the links between inflammation and metabolism with the added angle of white blood cell production. She is co-author on numerous publications in high-ranking journals in the fields of diabetes and metabolism including Journal of Clinical Investigation, Cell Metabolism and Nature Communications. Dr Kammoun is also an Adjunct Lecturer in the Central Clinical School, Monash University.

Research Interest

Haematopoiesis and Leukocyte Biology

Publications

  • Hélène Kammoun,Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance Cell Metabolism 2015;21(3):403–16.

  • Hélène Kammoun,PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications Nature Communications 2016;7:10626.

  • Hélène Kammoun,IL-18 production from the NLRP1 inflammasome prevents obesity and metabolic syndrome Cell Metabolism 2016;23(1):155–64.

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