Claudia
Vice President of Manufacturing
Pharmaceutical Sciences
Benitec Biopharma
Australia
Biography
Dr. Kloth leads the manufacturing efforts for clinical and pre-clinical gene therapy vectors for Benitec. Dr. Kloth has over 20 years of cGMP manufacturing and process development experience in therapeutics, including adeno-associated virus (AAV) vectors used by Benitec in its hepatitis C, hepatitis B, AMD and OMPD programs. Prior to joining Benitec, Dr. Kloth led the Process Development group at the CMO Lonza Viral Therapeutics and successfully developed, optimized and transferred robust viral-based products (Ad5, AAV, lentivirus) to cGMP manufacturing. She contributed to enabling process scalability from small to large manufacturing scale of over 1000L using disposable technologies. She was also instrumental in establishing a scalable AAV process production platform.
Research Interest
Pharmaceutical Sciences
