Andrew Guy
PhD Student
Life Sciences
Burnet Institute
Australia
Biography
Andrew’s work is focused on the characterisation of antibody responses against unstructured proteins from the malaria parasite. This involves a combination of computational biology and laboratory based epitope-mapping techniques. This work hopes to identify new targets of protective immunity which can be used as potential vaccine targets.
Research Interest
Disease Elimination Maternal and Child Health
Publications
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Acquisition of functional antibodies that block the binding of erythrocyte binding antigen 175 and protection against Plasmodium falciparum malaria in children. Irani V, Ramsland PA, Guy AJ, Siba PM, Mueller I, Richards JS, Beeson JG Clin Infect Dis. 2015 Jul; 61(8):1244-1252
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Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions. Guy AJ, Irani V, MacRaild CA, Anders RF, Norton RS, Beeson JG, Richards JS, Ramsland PA PLoS One. 2015 Oct; 10(10):e0141729
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Maternal-foetal transfer of Plasmodium falciparum and Plasmodium vivax antibodies in a low transmission setting. Charnaud SC, McGready R, Herten-Crabb A, Powell R, Guy A, Langer C, Richards JS, Gilson PR, Chotivanich K, Tsuboi T, Narum DL, Pimanpanarak M, Simpson JA, Beeson JG, Nosten F, Fowkes FJ Sci Rep. 2016 Feb; 6:20859