Jessica Anania
PhD Student
Life Sciences
Burnet Institute
Australia
Biography
Jessica Anania is a PhD student, Hogarth Laboratory, Burnet Institute, Melbourne.
Research Interest
My key research interest is the role of antibodies and their receptors in the human immune system, in particular a newly described Fc receptor variant in people with autoimmune disease. My work is investigating the functions of the receptor, its cellular distribution, specificity for antibodies and determining differences in its signalling pathways. My aim is to determine how this previously unknown receptor induces inflammation and whether it is a suitable disease biomarker or therapeutic monoclonal antibody target.
Publications
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The FcγR of humans and non-human primates and their Interaction with IgG: Implications for induction of inflammation, resistance to infection and the use of therapeutic monoclonal antibodies. Hogarth PM, Anania JC, Wines BD Curr Top Microbiol Immunol. 2014 Aug; 382:321-352