Joshua Hayward
Research Officer
Life Sciences
Burnet Institute
Australia
Biography
My thesis examined the antiviral defenses of bats, which are a significant source of viruses deadly to humans, and their history of infection with retroviruses. It identifies that bats have been host to a highly diverse range of retroviruses and finds that these viruses have been transmitted to other mammals. Bats are revealed to have unique features in their antiviral immune system that may give them an enhanced ability to control viral infections. This research was undertaken within the Retroviral Biology and Antivirals Research Laboratory, led by Assoc. Prof. Gilda Tachedjian.
Research Interest
My work involves analyses of the microbiome within the female reproductive tract and the metabolites that they produce, with respect to their impact on sexually transmitted infections. I am also working toward the identification and characterisation of novel retroviruses in Australian mammals.
Publications
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Identification of diverse full-length endogenous betaretroviruses in megabats and microbats. Hayward JA, Tachedjian M, Cui J, Field H, Holmes EC, Wang LF, Tachedjian G Retrovirology. 2013 Mar; 10(1):35
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Bats and Reverse Transcribing RNA and DNA Viruses (Book Chapter) Tachedjian G, Hayward JA, Cui J in Bats and Viruses: A New Frontier of Emerging Infectious Diseases, Editors LF Wang and C Cowled, Published by Wiley. 2015 Jul; Chapter 7 :177-202
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Increasing Prevalence of Synonymous Mutations K65K and K66K in HIV-1 subtype B reverse transcriptase. Telwatte S, Brumme CJ, Hearps AC, Latham CF, Hayward JA, Sonza S, Sluis-Cremer N, Harrigan PR, Tachedjian G AIDS. 2016 Sep; 30(18):2787-2793
