Michelle Boyle
Researcher
Life Sciences
Burnet Institute
Australia
Biography
Michelle completed her PhD with Professor James Beeson in 2012 with a focus on developing methods to study Plasmodium falciparum malaria parasite invasion of red blood cells. These studies included investigating mechanisms and inhibitors of invasion with a focus on progress towards vaccine and drug development. Michelle received a Victorian Premier’s Award for Health and Medical Research Commendee Award for these studies in 2013
Research Interest
Michelle is an Honorary Fellow at the Menzies School of Health Research in Darwin, as well as a Research Officer at Burnet Institute. She is working on collaborative projects between the two institutes to identify mechanisms contributing to the acquisition of immunity against multiple malaria species in the South East Asia region.
Publications
-
Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure. Jagannathan P, Lutwama F, Boyle MJ, Nankya F, Farrington LA, McIntyre TI, Bowen K, Naluwu K, Nalubega M, Musinguzi K, Sikyomu E, Budker R, Katureebe A, Rek J, Greenhouse B, Dorsey G, Kamya MR, Feeney ME Sci Rep. 2017 Sep; 7(1):11487
-
The development of Plasmodium falciparum-specific IL10 CD4 T cells and protection from malaria in children in an area of high malaria transmission. Boyle MJ, Jagannathan P, Bowen K, McIntyre TI, Vance HM, Farrington LA, Schwartz A, Nankya F, Naluwu K, Wamala S, Sikyomu E, Rek J, Greenhouse B, Arinaitwe E, Dorsey G, Kamya MR, Feeney ME Front Immunol. 2017 Oct; 8:1329
-
Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development. Boyle MJ, Skidmore M, Dickerman B, Cooper L, Devlin A, Yates E, Horrocks P, Freeman C, Chai W, Beeson JG Antimicrob Agents Chemother. 2017 Oct; 61(11): e00709-17
