Andre Minoche
Research Officer
Clinical Genomics
Garvan Institute of Medical Research
Australia
Biography
André completed his Master of Science in Biotechnology at the École supérieure de biotechnologie Strasbourg in 2008, a trinational biotech school in the heart of Europe. After that he did a PhD in Bioinformatics in affiliation with the Max Planck Institute for Molecular Genetics, Berlin, Germany and the Centre for Genomic Regulation, Barcelona, Spain. During his PhD, André assembled complex genomes de novo, annotated them and investigated the genome sequence variability and genome evolution. He completed his PhD with magna cum laude in 2013, published his main research work in Nature, and joined the Garvan Institute in 2014.
Research Interest
Medical genetics - Discover the genetic component of human diseases from massive parallel sequencing data. Pharmacogenomics - Predict drug responses from the genome sequence Genome evolution
Publications
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Dohm, J.C., Minoche, A.E., Holtgräwe, D., Capella-Gutiérrez, S., Zakrzewski, F., Tafer, H., Rupp, O., Sörensen, T.R., Stracke, R., Reinhardt, R., et al. (2014). The genome of the recently domesticated crop plant sugar beet (Beta vulgaris). Nature 505, 546–549.
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Minoche, A.E., Dohm, J.C., and Himmelbauer, H. (2011). Evaluation of genomic high-throughput sequencing data generated on Illumina HiSeq and genome analyzer systems. Genome Biol. 12, R112.
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Montagut, C., Dalmases, A., Bellosillo, B., Crespo, M., Pairet, S., Iglesias, M., Salido, M., Gallen, M., Marsters, S., Tsai, S.P., et al. (2012). Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer. Nat. Med. 18, 221–223.
