Martin Smith
Clinical Genomics
Garvan Institute of Medical Research
Australia
Biography
I am a computational biologist with a strong background in biology. As a child growing up in Canada, I always dreamt of becoming a biologist. I majored as an undergraduate in microbiology and immunology at the University of Montreal, however I quickly realised this wasn’t my field. Switching to the emerging field of bioinformatics was an enthusiastic yet challenging decision for me, as it required rewiring my brain around abstract informatics concepts and discrete mathematics.
Research Interest
Oxford Nanopore Sequencing, Bioinformatics, Comparative genomics, Transcriptomics, RNA secondary structure, noncoding RNA
Publications
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Khaitan D, Dinger ME, Mazar J, Crawford J, Smith MA, Mattick JS, Perera RJ. The Melanoma-Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion. Cancer Research, 2011, 71(11):3852-62
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Shore AN, Kabotyanski EB, Roarty K, Smith MA, Zhang Y, Creighton CJ, Dinger ME, Rosen JM. Pregnancy-Induced Noncoding RNA (PINC) Associates with Polycomb Repressive Complex 2 and Regulates Mammary Epithelial Differentiation. PLoS Genetics, 2012, 8(7): e1002840
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Smith MA, Gesell T, Stadler PF, Mattick JS. Widespread purifying selection on RNA structure in mammals. Nucleic Acids Research, 2013, 41 (17): 8220-8236