Samantha Oakes
Cell Survival
Garvan Institute of Medical Research
Australia
Biography
Dr. Samantha Oakes is head of the Cancer Cell Survival group at the Garvan Institute of Medical Research and Conjoint Senior Lecturer, St Vincent's Clinical School, UNSW Sydney. In 2007, Samantha received her PhD from the University of New South Wales and won the Garvan Institute best thesis prize for this work. Since this time, Samantha has published 25 research manuscripts focused on the understanding and treatment of cancer and has been awarded over $3.2 million in competitive grant funding. The focus of her lab is to understand the molecular and mechanistic signals involved in breast cancer tumour cell survival. The mechanisms that contribute to cell survival underlie every stage of tumour progression from the initiating event, tumour growth, localised invasion and metastasis and finally during the acquisition of chemotherapeutic resistance. These mechanisms can arise from the tumour cell itself (intrinsic) or act in concert with the microenvironment (extrinsic).
Research Interest
Cell survival Apoptosis Cancer biology Cancer genetics Breast cancer Cancer therapy Cancer research Mammary development Stem cells