Caroline Gargett
Professor
The Ritchie Centre
Hudson Institute of Medical Research
Australia
Biography
Professor Gargett (PhD 1997) is world-renowned for her discovery of stem/progenitor cells in human endometrium, the highly regenerative lining of the uterus, publishing the first paper in 2004. She established the Endometrial Stem Cell Biology Group at the same time when she was awarded the top scoring NHMRC New Investigator grant to investigate their biology.
Research Interest
Her current research characterises these endometrial stem/progenitor cells and examines their role in endometriosis, endometrial-related infertility, and endometrial cancer. She leads a transdisciplinary project in collaboration with CSIRO Manufacturing, Flinders University Biomedical Engineering, Monash Engineering and urogynaecologists to investigate the use of endometrial mesenchymal stem/stromal cells for a tissue engineering application in pelvic floor prolapse surgery. Her research findings are promising for the development of potential therapeutics.
Publications
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Gurung S, Werkmeister JA, Gargett CE (2015) Inhibition of Transforming Growth Factor-β Receptor signaling promotes culture expansion of undifferentiated human Endometrial Mesenchymal Stem/stromal Cells. Scientific Reports 5:15042
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Deane JA, Ong YR, Cain JE, Jayasekara WS, Watkins DN, Carlone D, Breault D, Gargett CE (2016) The mouse endometrium contains epithelial, endothelial and leukocyte populations expressing the stem cell marker telomerase reverse transcriptase. Molecular Human Reproduction 22:272-284.
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Gargett CE, Schwab KE, Deane JA (2016) Endometrial Stem/progenitor cells: the first 10 years. Human Reproduction Update 22:137-163 (IF11.194; 19 citations)
