Dr Bryan Leaw
Postdoctoral Scientist
The Ritchie Centre
Hudson Institute of Medical Research
Australia
Biography
Dr Leaw is a neuroscientist who joined Professor Euan Wallace’s research group in The Ritchie Centre at the Hudson Institute of Medical Research in October 2014 after completing his PhD at the University of Melbourne. Dr Leaw has won numerous awards during his scientific studies. His PhD thesis was ranked top in the University of Melbourne’s Department of Anatomy and Neuroscience, and his PhD was subsequently nominated for the Chancellor’s Prize in PhD Excellence.
Research Interest
Dr Leaw has two research aims: assessing potential new therapies in the treatment of pre-eclampsia and assessing the therapeutic benefit of human amnion epithelial cells in the treatment and prevention of cerebral palsy. Dr Leaw was recently awarded a $141,980 project grant from the Cerebral Palsy Alliance to address his second aim, and has recently uncovered neuroprotective properties of amnion cells. He now aims to further this research by applying amnion cells to a variety of preclinical models of cerebral palsy to elucidate improvements in long-term motor and cognitive behavioural outcomes
Publications
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Leaw B, Reid CA, Richards KL, Richardson R, Wimmer V, Low J, Hill-Yardin E, Lerche H, Scheffer IE, Berkovic SF, Petrou S. Reduced dendritic arborisation and hyperexcitability of pyramidal neurons in a Scn1b¬-based model of Dravet syndrome. Brain. 2014 Jun;137(Pt 6):1701-15.
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Gazina EV, Leaw BT, Richards KL, Wimmer VC, Kim TH, Aumann TD, Featherby TJ, Churilov L, Hammond VE, Reid CA, Petrou S. ‘Neonatal’ Nav1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour. Hum Mol Genet. 2015 Mar 1;24(5):1457-68
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Lim R, Adhikari S, Gurusinghe S, Leaw B, Acharya R, Rahman R, Ciayadi R, Potdar M, Kelso GF, Hearn MT, Wallace EM. Inhibition of activin A signalling in a mouse model of pre-eclampsia. Placenta. 2015 Aug; 36(8):926-31.
