Dr Daniel Gough

Biography

Dr Daniel Gough is Head of the STAT Cancer Biology research group in Hudson Institute’s Centre for Cancer Research and a Chief Investigator for the Paediatric Precision Medicine Program. After completing his BSc (2000) and BSc (Hons) (2001) in the Department of Pathology at the University of Melbourne, and PhD (2006) at the Peter MacCallum Cancer Centre, Dr Gough moved to New York University in the USA for postdoctoral training with Professor David E Levy (Dr Louis A. Schneider Professor of Molecular Pathology and Professor of Microbiology, and Associate Dean for Collaborative Science). During this time Dr Gough defined a mitochondrial and metabolic role for STAT3, which is necessary for cancers driven by Ras mutation. In 2012, Dr Gough was recruited to return to Australia to start his laboratory where he and his team use protein chemistry, molecular biology, animal models and human tissue to identify actionable alterations in cell signalling networks that drive cancers.

Research Interest

A biochemist and cancer biologist, Dr Gough’s research focuses on signal transduction pathways, which engage the Signal Transducer and Activator of Transcription (STAT) proteins in normal development, and how these pathways are altered in childhood cancers.