Bon-kyoung Koo
Group LeaderĂ‚Â
Department of Molecular Biotechnology
Institute of Molecular Biotechnology
Australia
Biography
"Education and employment Oct 2017 – Appointed Group Leader, IMBA, Vienna, Austria Apr 2013 – Sep 2017 Group Leader, Cambridge Stem Cell Institute, Univ. of Cambridge Mar 2009 – Apr 2013 Postdoctoral fellow, Hubrecht Institute, KNAW, the Netherlands (Mentor: Prof. Hans Clevers) Mar 2006 – Feb 2009 Postdoctoral fellow, Pohang University of Science and Technology (POSTECH) and Seoul National University (Mentor: Prof. Young-Yun Kong) Mar 2002 – Feb 2006 Ph.D., Div. of Mol. and Lif. Sci., POSTECH, Republic of Korea (Advisor: Prof. Young-Yun Kong) Mar 2000 – Feb 2002 M.S. Div. of Mol. and Lif. Sci., POSTECH, Republic of Korea Mar 1996 – Feb 2000 B.S. Dept. of Lif. Sci., POSTECH, Republic of Korea iii. Professional activities 2016 A member of the organising committee – EMBO Wnt meeting 2016 2016 – Present Adj. Professor at Pohang Univ. of Science & Tech (POSTECH), South Korea 2016 Main editor for DB Special Issue on Organoids (Developmental Biology) 2015 – Present A member of the steering committee – BiKiE (Bio Korea in Europe) 2015 – Present Affiliate PI at Cambridge Cancer Centre 2015 – Present Main Instructor at the Sanger Institute’s Advanced Course – Genetic Engineering of Mammalian Stem Cells 2015 – Present Main Instructor at the Cambioscience Workshop – Mouse Intestinal Organoids – Establishment, Culture & Manipulation 2015 – Present Part II Lectures in Dept. of Genetics, Univ. of Cambridge 2015 – Present ERC investigator – European Research Council 2014 – Present Affiliate PI at Centre for Trophoblast Research 2013 – Present Faculty member at the Dept. of Genetics, Univ. of Cambridge 2013 – Present Partner PI – WntsApp – Marie Curie ITN programme 2013 – Present Sir Henry Dale Fellow – Wellcome Trust & Royal Society iv. Fellowships and grants 2016 CRUK - Multidisciplinary Project Award Tracing the cellular basis of cancer development (£499,898) 2015 ERC starting grant – Troy Stem Cells, European Research Council (€1,570,399) 2013 Marie Curie Initial Training Network – WntsApp, WNT-mediated signalling relay in stem cells and oncogenesis - from basic biology to applications. (£486,113) 2013 Sir Henry Dale Fellowship, the Wellcome Trust & the Royal Society (£1,075,543) 2012 Wellcome Trust Recruitment Enhancement, the Wellcome Trust (£500,000) (Returned after the award of Sir Henry Dale Fellowship) 2011 Fostering next-generation researchers program, The National Research Foundation of Korea Fellowship: NRF-2011-357-C00093 (KRW 32,000,000 = £18,285) v. Awards 2012 Travel Award, EMBL Conference Stem Cells in Cancer and Regenerative Medicine 2007 Poster Award, 64th KSBMB Annual Meeting in 2007 and 19th FAOBMB Seoul Conference (International Conference) Curriculum Vitae (Bon-Kyoung Koo) 2 vi. Patents 2016 Patent application No. 1613839.8, Conditional Gene Targeting Method 2009 Patent number: 8076532, Transgenic mouse defective in WW45 function and use in screening compounds for anti-tunour activity"
Research Interest
HOMEOSTATIC REGULATION OF ADULT STEM CELLS
Publications
-
2017 One-step generation of conditional and reversible gene knockouts. Nat Methods Andersson-Rolf, A., Mustata, RC., Merenda, A., Kim, J., Perera, S., Grego, T., Andrews, K., Tremble, K., Silva, JC., Fink, J., Skarnes, WC., Koo, BK."
-
2017 Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium. Nat Cell Biol Turco, MY., Gardner, L., Hughes, J., Cindrova-Davies, T., Gomez, MJ., Farrell, L., Hollinshead, M., Marsh, SGE., Brosens, JJ., Critchley, HO., Simons, BD., Hemberger, M., Koo, BK., Moffett, A., Burton, GJ.
-
"2017 A Protocol for Multiple Gene Knockout in Mouse Small Intestinal Organoids Using a CRISPR-concatemer. J Vis Exp Merenda, A., Andersson-Rolf, A., Mustata, RC., Li, T., Kim, H., Koo, BK.
