Fumiyo Ikeda

Biography

"Fumiyo Ikeda Nationality Japan Research experiences Since 2011 Junior group leader, IMBA, Vienna, Austria 2010-2011 Staff scientist, Goethe-Univ. Frankfurt aM, Germany (Dikic Lab) 2005-2010 Postdoctoral fellow, Goethe-Univ. Frankfurt aM, Germany (Dikic Lab) 2003-2005 Staff scientist, Osaka Univ., Graduate School of Dentistry, Japan (Yoneda Lab) 2000-2003 Research assistant, Osaka Univ., Graduate School of Dentistry, Japan (Yoneda Lab) Educations 1999-2003 Osaka Univ., Graduate School of Dentistry, Japan Major Molecular Biology Degree Ph. D. 1993-1999 Osaka Univ., Dental School, Japan Major Dentistry Degree D.D.S. (Doctor of Dental Science). From postdoc works: Ikeda F, Deribe YL, Skånland SS, Stieglitz B, Grabbe C, Franz-Wachtel M, van Wijk SJ, Goswami P, Nagy V, Terzic J, Tokunaga F, Androulidaki A, Nakagawa T, Pasparakis M, Iwai K, Sundberg JP, Schaefer L, Rittinger K, Macek B, Dikic I (2011). SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Nature. 471(7340):637-41 Ikeda F, Crosetto N, Dikic I (2010). What determines the specificity and outcomes of ubiquitin signaling? Cell. 143(5):677-81 Rahighi S*, Ikeda F*, Kawasaki M, Akutsu M, Suzuki N, Kato R, Kensche T, Uejima T, Bloor S, Komander D, Randow F, Wakatsuki S# , Dikic I# (2009). Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. Cell. 136(6):1098-109, *equal contribution, # correspondence Ikeda F# , Dikic I# (2008) Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series. EMBO Rep. 9(6):536-42, # correspondence From PhD works: Ikeda F, Nishimura R, Matsubara T, Hata K, Reddy SV, Yoneda T (2006) Activation of NFAT signal in vivo leads to osteopenia associated with increased osteoclastogenesis and bone-resorbing activity. J Immunol 177: 2384-2390 Ikeda F, Nishimura R, Matsubara T, Tanaka S, Inoue J, Reddy SV, Hata K, Yamashita K, Hiraga T, Watanabe T, Kukita T, Yoshioka K, Rao A, Yoneda T (2004) Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. J Clin Invest 114: 475-484 Grants ERC consolidator grant ‘LUbi’ (614711), since 2014 FWF grant ‘Programmed cell death control by SHARPIN’ (P25508), since 2013 COST European network grant ‘PROTEOSTASIS’ (BM1307), since 2014 Fellowships 2008-2010 Japan Society for the Promotion of Science, JSPS Postdoctoral Fellowship for Research Abroad (Japan) 2005-2007 The Alexander von Humboldt Foundation, Research Fellowship (Germany) 2005 The Uehara Memorial Foundation, Research Fellowship for Research Abroad (Japan) 2002-2003 The Iwadare Scholarship Foundation, Research Fellowship for PhD program (Japan) 1999-2003 The Japan Scholarship Foundation, Research Fellowship for PhD program (Japan) Prizes and Awards 2011 Poster award, 3rd EMBO meeting, Vienna, Austria 2011 Travel award, 13th TNF international conference, Hyogo, Japan 2010 Dr. Paul und Cilli Weill Foundation Award, Goethe-Univ Frankfurt aM, Germany 2003 two Young Investigator Awards, The American Society for Bone and Mineral Research, USA Teaching 2014-present Vienna Univ., Biochemie Proseminar (300 051) 2005-2011 Goethe-Univ. Frankfurt aM, Medical school, practical courses (Protein, hormone) Supervision PhD thesis: Petra Ebner (2013-2017), Younes Redouane (2013-2016) Master thesis: Jorge Almagro (2016-2017), Isabella Poetsch (2015-2017), Christine Ehrhardt (2013-2014), Stefan Lutzmayer (2012-2013) "

Research Interest

LINEAR UBIQUITINATION IN INFLAMMATION, CELL DEATH AND AUTOPHAGY