Sasha Mendjan
GROUP LEADER
Department of Molecular Biotechnology
Institute of Molecular Biotechnology
Australia
Biography
Senior postdoc, Vallier lab, SCI, University of Cambridge, UK 2013-2015 Postdoc, Pedersen lab, LRM, University of Cambridge, UK 2007-2013 PhD – Akhtar lab, EMBL and University of Heidelberg, Germany 2002-2006 Diploma degree, thesis in Grosschedl lab, Ludwig Maximilian University, Munich, Germany 1997-2002
Research Interest
MOLECULAR CONTROL OF HUMAN ORGANOGENESIS
Publications
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Mendjan S, Taipale M, Kind J, Holz H, Gebhardt P, Schelder M, Vermeulen M, Buscaino A, Duncan K, Mueller J, Wilm M, Stunnenberg HG, Saumweber H, Akhtar A. (2006). Molecular Cell. 145 citations. Nuclear Pore Components are Involved in the Transcriptional Regulation of Dosage Compensation in Drosophila We co-purified nuclear pore proteins with chromatin complexes. This work led to other high impact studies.
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Bertero A, Madrigal P, Galli A, Hubner NC, Moreno I, Burks D, Brown S, Pedersen RA, Gaffney D, Mendjan S*, Pauklin S*, Vallier L*. (2015). Co-senior*. Genes & Development. ACTIVIN Signalling Governs Pluripotency by Shaping the H3K4me3 Epigenetic Landscape We identified DPY30 as the missing link that connects SMAD2/3 signalling and key epigenetic marks.
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Mendjan S, Mascetti VL, Ortmann D, Ortiz M, Karjosukarso D, Ng Y, Moreau T & Pedersen RA. (2014). Co-corresponding author. Cell Stem Cell. NANOG and CDX2 Pattern Distinct Subtypes of Human Mesoderm during Exit from Pluripotency We discovered how different ways to induce mesoderm lead to distinct mesodermal lineages and tissues.
