Bruce Trapp
Director
Neuroscience
Lerner Research Institute
Australia
Biography
The aim of Dr. Trapp's lab is to obtain a better understanding of cellular/molecular events that regulate production and differentiation of oligodendrocytes and central nervous system (CNS) myelination. Using transgenic mice, they study the role of myelin and myelin proteins in maintaining axonal function and survival. They also investigate the role of CNS progenitor cells as a source of new oligodendrocytes in the adult brain. A common theme of these research programs is that novel information about the normal function of myelin-forming cells and myelin-axon interactions will help them understand the mechanisms involved in human diseases that destroy myelin or myelin-forming cells.
Research Interest
CNS, Astrocytes, Neuro protection