Oliver Sieber
Director, Oliver Sieber Lab
Oliver Sieber Lab Ludwig Center at Melbourne
Ludwig Institute for Cancer Research
Australia
Biography
I am an Assistant Member of the Ludwig Institute and Human Geneticist and Laboratory Head at the Walter and Eliza Hall Institute of Medical Research in Melbourne. I received my undergraduate degree from University College London, followed by PhD studies on the genetic basis of bowel tumor (colorectal cancer) syndromes in the Molecular and Population Genetics Laboratory, Cancer Research UK. I then undertook post-doctoral training at the Cancer and Immunogenetics Laboratory for Cancer Research UK in Oxford and later at the Ludwig Institute for Cancer Research in Melbourne. I was Joint Laboratory Head at the Ludwig Institute for Cancer Research from 2009 to 2012, when I moved my laboratory to the Walter and Eliza Hall Institute of Medical Research. My group aims to improve outcomes for patients with bowel cancer by identifying molecular markers, such as particular gene mutations or gene expression profiles, that have the potential to improve diagnosis and prognosis and guide clinical treatment decisions. I have published more than 60 scientific papers and book chapters and am actively involved in graduate student supervision and peer-review activities.
Research Interest
Bowel cancer, molecular markers, gene mutations
Publications
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Sieber, Oliver M., Karl Heinimann, and Ian PM Tomlinson. "Opinion: Genomic instability--the engine of tumorigenesis?." Nature reviews. Cancer 3.9 (2003): 701.
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Broderick, Peter, et al. "A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk." Nature genetics 39.11 (2007): 1315-1317.
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Broderick, Peter, et al. "A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk." Nature genetics 39.11 (2007): 1315-1317.