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Julie Atkin


DEPARTMENT OF BIOMEDICAL SCIENCES
Macquarie University
Australia

Biography

A/Prof Atkin a neuroscientist and cell biologist with an international reputation in the field of ALS/MND. Her work involves identification of the major cellular signalling pathways that trigger motor neuron death in ALS/MND, and how these pathways can be modulated. This work aims to develop novel therapeutic strategies for ALS/MND, based on inhibiting the fundamental mechanisms that trigger neurodegeneration in this disorder.

Research Interest

Molecular and cellular mechanisms leading to neurodegeneration in ALS/MND and FTD. Modulation of Endoplasmic Recticulum homeostasis as a novel therapeutic strategy in ALS/MND Structural and functional properties of proteins relevant to ALS/MND

Publications

  • Turner BJ, Atkin JD, Farg MA, Zang DW, Rembach A, Lopes EC, Patch JD, Hill AF, Cheema SS. Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis. Journal of Neuroscience. 2005 Jan 5;25(1):108-17.

  • Atkin JD, Farg MA, Walker AK, McLean C, Tomas D, Horne MK. Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis. Neurobiology of disease. 2008 Jun 30;30(3):400-7.

  • Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2016 Jan 2;12(1):1-222.

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