Mark (scott) Baker
DEPARTMENT OF BIOMEDICAL SCIENCES
Macquarie University
Australia
Biography
Mark is the current HUPO President and is a cancer researcher with an international reputation in the fields of proteomics, colorectal cancer biology and the roles of cell-surface membrane protein-protein interactions in cancer spread (metastasis). Mark is active in many aspects around the Human Proteome Project. His work combines molecular cell biology with the latest in mass spectrometry and protein interaction technologies, to better comprehend the role of proteins and signalling pathways disturbed in cancer. This work has led to novel actionable cancer cell-surface therapeutic targets, as well as the development of candidate cancer biomarker diagnostics.
Research Interest
Role of uPAR-integrin interactions in switching cancer cell signaling towards metastasis. Early stage colorectal cancer advanced mass spectrometric diagnostic assays The Human Proteome Project’s “missing proteins” Food proteomics: understanding how humans savour olfaction
Publications
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Berka RM, Grigoriev IV, Otillar R, Salamov A, Grimwood J, Reid I, Ishmael N, John T, Darmond C, Moisan MC, Henrissat B. Comparative genomic analysis of the thermophilic biomass-degrading fungi Myceliophthora thermophila and Thielavia terrestris. Nature biotechnology. 2011 Oct 1;29(10):922-7.
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Baker SE, Hopkinson SB, Fitchmun M, Andreason GL, Frasier F, Plopper G, Quaranta V, Jones JC. Laminin-5 and hemidesmosomes: role of the alpha 3 chain subunit in hemidesmosome stability and assembly. Journal of Cell Science. 1996 Oct 1;109(10):2509-20.
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Haussler D, O'Brien SJ, Ryder OA, Barker FK, Clamp M, Crawford AJ, Hanner R, Hanotte O, Johnson WE, McGuire JA, Miller W. Genome 10K: a proposal to obtain whole-genome sequence for 10 000 vertebrate species.
