Salvatore Pepe
Professor
Clinical Sciences
Murdoch Childrens Research Institute
Australia
Biography
A/Prof Salvatore Pepe initially trained in clinical pharmacology and biochemistry. After completing a PhD in cardiac physiology he undertook four years of postdoctoral training as a National Institutes of Health, National Institute of Aging, Fogarty Fellow at Johns Hopkins Bayview Medical Center, Baltimore, USA. Before joining Murdoch Childrens, he was Head of the Laboratory of Cardiothoracic Surgical Research, Department of Cardiothoracic Surgery, Alfred Hospital and Adjunct Senior Lecturer, Department of Surgery, Monash University. A/Prof Pepe's research has been focused on dysfunctional mitochondrial metabolism in heart disease injury, therapeutic targets in heart failure, and cardioprotection in heart transplantation and cardiopulmonary bypass surgery. In mid-2008 he was invited to move his laboratory to the Murdoch Childrens to undertake the challenge of paediatric heart research.
Research Interest
Paediatrics,Pharmacology and Physiology,Cellular & Molecular Cardiology
Publications
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Pepe S, Mentzer RM, Gottlieb RA. Cell-permeable protein therapy for complex I dysfunction. Journal of bioenergetics and biomembranes. 2014 Aug 1;46(4):337-45.
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Brizard CP, Looi JY, Smolich JJ, Horton SB, Angerosa J, Elwood NJ, Pepe S. Safety of intracoronary human cord blood stem cells in a lamb model of infant cardiopulmonary bypass. The Annals of thoracic surgery. 2015 Sep 30;100(3):1021-9.
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Sheeran FL, Pepe S. Posttranslational modifications and dysfunction of mitochondrial enzymes in human heart failure. American Journal of Physiology-Endocrinology and Metabolism. 2016 Aug 1;311(2):E449-60.
